OBJECTIVE To determine the sensitivity and specificity of thallium scintigraphy in detection of coronary artery disease in diabetic patients. STUDY DESIGN Cross-sectional validation study. PLACE AND DURATION OF STUDY The study was carried out from July to December 2007 in the Cardiology Department of the Pakistan Institute of Medical Sciences, Islamabad. METHODOLOGY A total of 60 diabetic...

Thallium is widely found in nature, but the only inorganic stones full of this element are crookesite and lorandit. It isalso found in pyrites of copper, lead and inorganic stones. The element and its compositions are toxic and harmful to theenvironment; therefore, its application requires caution and further research. It is important to develop sensitive andaccurate analytical methods to deter...

Serial myocardial imaging after a single dose of thallium is often used in evaluating patients with coronary artery disease. Because the appearance of the image is related to myocardial thallium content, it is important to know if transient ischemia occurring after tracer administration will influence the rate of myocardial thallium clearance. To answer this question 13 mongrel dogs (eight stud...

BACKGROUND The clinical significance and pathophysiological mechanisms of reverse redistribution on stress-redistribution thallium-201 myocardial scintigraphy in patients with chronic coronary artery disease are unclear. Recent studies have shown that thallium-201 reinjection is a useful technique for the detection of myocardial viability in chronic coronary artery disease. In this investigatio...

Serial myocardial imaging after a single dose of thallium is often used in evaluating patients with coronary artery disease. Because the appearance of the image is related to myocardial thallium content, it is important to know if transient ischemia occurring after tracer administration will influence the rate of myocardial thallium clearance. To answer this question 13 mongrel dogs (eight stud...

backgrounds: thallium-201 is produced through 203tl (p, 3n) 201pb 201tl reaction by cyclotron. this radioisotope has known as one of the cyclotron radioisotopes which is used for myocardial perfusion in the coronary artery disease, tl-201 after chemical purification and quality control in the form of 201tl-chlorid is ready to send to the hospitals. materials and methods: in this work the effect...

Thallium is a highly toxic metal and predominantly hosted by sulfides associated with low-temperature hydrothermal mineralization. Weathering oxidation of generate acid drainage high concentration thallium, posing threat to surrounding environments. may also be incorporated into secondary sulfate minerals, which act as temporary storage for thallium. We present state-of-the-art review on the fo...

BACKGROUND Cardiac output is effectively redistributed to working muscle by regional changes in vascular resistance. However, there has been no suitable method to quantify blood flow distribution to large working and nonworking muscles involved in ergometer or treadmill exercise. METHODS AND RESULTS To quantify the redistribution of blood flow, we compared thallium activity in a bicycle pedal...

BACKGROUND In patients with coronary artery disease, stress-redistribution-reinjection thallium scintigraphy provides important information regarding myocardial ischemia and viability. Although both reversible and mild-to-moderate irreversible thallium defects retain metabolically active, viable myocardium, we hypothesized that stress-induced reversible thallium defects may better differentiate...

To determine if thallium-201 imaging of myocardial perfusion can be used as an early predictor of myocardial salvage after reperfusion, 24 adult dogs were subjected to complete occlusion of the left anterior descending coronary artery with release of the snare 2 hr later. Separate doses of thallium (1 mCi) and microspheres were given 15 min before, 5 min after, and 1 hr after release of the sna...