Monoclonal antibody (McAb) Po66 has been obtained by immunisation of mice against a human lung squamous cell carcinoma. The in vitro reactivity of the antibody with cancer cells and its ability to localise in human lung cancer xenografts growing in nude mice have been reported earlier. Presented here is the first clinical evaluation of the antibody for scintigraphic detection of tumours. Thirty...

D the 1950s, inmates at what was then called Holmesburg Prison, in Philadelphia, were inoculated with condyloma acuminatum, cutaneous moniliasis, and viruses causing warts, herpes simplex, and herpes zoster.1 For participating in this research, and in studies exposing them to dioxin and agents of chemical warfare, they were paid up to $1,500 a month. Between 1963 and 1971, researchers in Oregon...

Scientific experiments significantly enhance the understanding of human-building interactions in building and engineering research. Recently, conducting virtual reality (VR) has gained acceptance popularity as an approach to studying interactions. However, little attention been given standardization experimentations. Proper can promote reusability, replicability, repeatability VR accelerate mat...

Every therapy has toxic and therapeutic windows, and defining the side effects of any new therapeutic modality is the first order of business in the development of a treatment. With transformative therapies such as cell-based approaches, treatment side effects can be unpredictable and unanticipated. In some cases, experimental data raise serious concerns that must be appropriately managed. In t...

Modern brain technology is a highly dynamic and innovative field of research with great potential for medical applications. Recent advances in recording neural signals from the brain by brain-machine interfacing presage new therapeutic options for paralyzed people by means of neural motor prostheses. This paper examines foreseeable ethical questions related to the research on brainmachine inter...

This study was conducted to ascertain the attitudes of first year medical students to human and animal experimentation, while undergoing a course in Muscle and Nerve experimental Physiology. At the time of administration of the questionnaire, students had been exposed to both human as well as animal experiments. Approximately 81% of the students preferred human experiments (P < 0.05). This pref...

Through the analysis of case studies of chimpanzees (Pan troglodytes troglodytes) in residence at a sanctuary, who previously sustained prolonged captivity and biomedical experimentation, we illustrate how human psychological models of diagnosis and treatment might be approached in great apes. This study reflects growing attention to ethical, scientific, and practical problems associated with p...

Human experimentation is important to the development of life science. There are so many problems brought about by human experimentation, which should be paid more attention to by law in order to protect the right of the subject. International as well as domestic laws are enacted in order to beat the illegitimate human experiment, while criminal countermeasures should be taken to redeem the fai...