Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool to enhance drug delivery wide variety of applications. Therapeutic ultrasound, such or combined with cavitating nuclei microbubbles, explored cross permeabilize different biological barriers. This ability access otherwise impermeable tissues the body makes combination and therapeutics very appealing si...

We have developed a portable high power ultrasound system with a very low output impedance amplifier circuit (less than 0.3 Omega) that can transfer more than 90% of the energy from a battery supply to the ultrasound transducer. The system can deliver therapeutic acoustical energy waves at lower voltages than those in conventional ultrasound systems because energy losses owing to a mismatched i...

This review discusses the development, current applications, and therapeutic potential of ultrasound contrast agents. Microbubbles containing gases act as true, intravascular indicators, permitting a noninvasive, quantitative analysis of the spatial and temporal heterogeneity of blood flow and volumes within the microvasculature. These shelled microbubbles are near-perfect reflectors of acousti...

background:   patellofemoral pain syndrome (pfps) is defined as pain surrounding the patella when sitting with bent knees for prolonged periods of time or when performing activities like ascending or descending stairs, squatting or   athletic activities. patella dislocation is not included in pfps.     purpose:   this review analyzes the evidence based conservative management of pfps.   methods...

The Journal of Therapeutic Ultrasound has been established to provide an open access, online venue for the exponentially growing body of work in biomedical ultrasound therapy.

BACKGROUND Skin function is dependent on its biomechanical characteristics, resistance, malleability, and elasticity. Therapeutic ultrasound may increase cutaneous malleability thus and optimize the rehabilitation process on specific diseases. The aim of this study is to evaluate possible alterations of biomechanical characteristics of the normal skin after therapeutic ultrasound application. ...

OBJECTIVE To know rheumatologists' opinion on the usefulness of ultrasound in diagnostic and therapeutic decision making as applied to rheumatic diseases. MATERIAL AND METHODS A National survey was sent to all rheumatology units in hospitals with at least 200 beds. The questionnaire included: a) general data, b) purpose and most common areas of ultrasound exploration and c) assessment of the ...

Aims: Testing ultrasound-mediated cavitation for enhanced delivery of the therapeutic antibody cetuximab to tumors in a mouse model. Methods: Tumors with strong EGF receptor expression were grown bilaterally. Cetuximab was coadministered intravenously nuclei, consisting either ultrasound contrast agent Sonovue or gas-stabilizing nanoscale SonoTran Particles. One two exposed focused ultrasound. ...

discussion splenic artery aneurysm is a very uncommon cause of page kidney and to our knowledge, it was the first case of its kind ever reported in the literature. introduction the page kidney is a rare phenomenon that refers to hypertension resulting from any external compression of a kidney by a hematoma, tumor, lymphocele, or urinoma. the activation of the renin-angiotensin-aldosterone syste...