abstract background immune thrombocytopenic purpura (itp) is a common autoimmune bleeding condition in children that is characterized by a decrease in the platelet count. the aims of this study were to define epidemiologic features of patients with primary itp who were admitted to mofid children's hospital, tehran, iran, in a 5-year period. methods we retrospectively studied the records of pati...

background: idiopathic thrombocytopenic purpura (itp) is a disease that commonly affects women of reproductive age and is associated with maternal and fetal complications. objective: the aim of the present study was to report the perinatal outcome in pregnant women with itp. materials and methods: twenty one pregnant women with itp admitted in a teaching hospital in tehran, from october 2008 to...

Seven non-splenectomized patients with chronic refractory idiopathic thrombocytopenic purpura were treated with danazol 800 mg daily. All were glucocorticoid failures and four were refractory to all additional previous therapy. Five patients benefited from danazol and in two sustained normal platelet counts, for over 44 and 51 months, were observed. We conclude that danazol is useful for long t...

Idiopathic thrombocytopenic purpura in children usually a self limiting disorder. It may follow a viral infection or immunisation and is caused by an inappropriate response of the immune system. About 20-30% of children will fail to remit over six months (chronic idiopathic thrombocytopenic purpura). This is more likely in older children, especially girls. The disease is reviewed with reference...

1. Scaradavou A, Woo B, Woloski BMR, Cunningham-Rundles S, Ettinger LJ, Aledort LM, Bussel JB: Intravenous anti-D treatment of immune thrombocytopenic purpura: Experience in 272 patients. Blood 89:2689, 1997 2. Salama A, Kiefel V, Amberg R, Mueller-Eckhardt C: Treatment of autoimmune thrombocytopenic purpura with Rhesus antibodies (antiD). Blut 49:29, 1984 3. Nance SJ, Arndt P, Garratty G: Pred...

INTRODUCTION Treatment of the rare cases of patients with chronic idiopathic thrombocytopenic purpura with acute coronary syndrome can be a significant problem. The patient in our case report was treated successfully with percutaneous coronary intervention. CASE PRESENTATION A 51-year-old man of Turkish origin who had idiopathic thrombocytopenic purpura was admitted to our hospital with sever...

BACKGROUND Corticosteroid or intravenous immunoglobulin is used in the management of idiopathic thrombocytopenic purpura during pregnancy. CASE PRESENTATION A patient with idiopathic thrombocytopenic purpura had a previous history of interrupted pregnancy due to severe thrombocytopenia, and was unresponsive to high doses of corticosteroids and intravenous immunoglobulin. Immediately following...

First described in 1916, idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease resulting in the destruction of platelets. Here, we present a case of an 85-year-old patient diagnosed with invasive ductal carcinoma of the breast whose surgical treatment was complicated postoperatively by acute-onset thrombocytopenia with a resultant hematoma at the operative site. Diagnostic Workup r...

Acute hepatitis due to hepatitis A virus is usually a benign selflimiting disease during childhood. Although many viral infections such as hepatitis B virus, Parvovirus, and Epstein-Barr virus are associated with extrahepatic autoimmune phenomena, such manifestations are rare in patients with acute hepatitis A infection. Immune thrombocytopenia is a benign, self-limiting disease in children, re...

Acute pancreatitis is an inflammatory condition marked by localized tissue damage that may lead to a broader reaction. There growing evidence patients with severe form of acute have endothelial dysfunction as one the key pathophysiologic symptoms. In line this, there been new studies linking hematological thrombotic thrombocytopenic purpura (TTP).Here, we are describing rare conversive event in...