Introduction: The combination of atezolizumab, an immune checkpoint inhibitor (ICI), and bevacizumab, a vascular endothelial growth factor (VEGF) inhibitor, is the first choice for systemic therapy in hepatocellular carcinoma. Immune-related cardiovascular toxicity—myocarditis pericarditis—are known to occur during ICI treatment. By contrast, VEGF inhibitors (VEGFIs) cause complications such as...

Background Graves' disease is a prevalent endocrine disorder characterized by diverse clinical manifestations affecting multiple organs, exhibiting varying degrees of severity. Cardiovascular system involvement one the most common manifestations, which include palpitation, tachycardia, cardiomyopathy, atrial fibrillation, pulmonary hypertension, or heart failure. Additionally, excessive thyroid...

The aim of the study was to evaluate the clinical usefulness of N-terminal pro-brain natriuretic peptide (NT-Pro BNP) and nitric oxide (NO) with echocardiography (gold standard test) in diagnosis of canine cardiomyopathy. Out of 374 cases, 82 cases showing cardiovascular abnormalities including 16 cases of cardiomyopathy were further selected for standardization of biomarkers. Significant (P

UNLABELLED The survival rate of cancer patients has greatly increased over the last 20 years. However, to achieve this result, a considerable price has been paid in terms of the side effects associated with the intensive anticancer treatment. The most common adverse effect is cardiotoxicity which may compromise the clinical effectiveness of chemotherapy, affecting the patient's survival and qua...

SECONDARY cardiomyopathy is defined as heart muscle disease of known cause or association. Naming particular diseases is preferable where individual conditions are being referred to e.g. myocardial sarcoid, cardiac amyloidosis, scleroderma heart disease, since the term cardiomyopathy without qualification is generally accepted as referring to the primary forms. Nevertheless, a convenient collec...

cocaine is used by more than 14 million people worldwide, about 0.3 percent of the global population age is 15 to 64 years. after alcohol, cocaine is the most common cause of acute drug-related emergency department visits in the united states. cocaine consumption is more frequently associated with acute cardiovascular illness.  cocaine stimulates α 1 , α 2 , β 1 and β 2 adrenergic receptors thr...

BACKGROUND Significant morbidities, including angina, symptomatic heart failure, and myocardial infarction, have been reported after coronary artery fistula (CAF) closure; however, predictors that may be associated with adverse outcomes have not been established. The goal of this investigation is to describe the long-term outcomes witnessed in patients with either treated or untreated CAF at ou...

colleagues in a recent issue of Critical Care [1]. Th ese authors emphasize the value of transthoracic echocardiography (TTE) for the diagnosis of intraventricular thrombosis in the postoperative period, especially in patients with dilated or ischemic cardiomyopathy. We believe that TTE is a noninvasive imaging technique useful in the context of critical care; but we must be honest about its li...

L eft ventricular assist device (LVAD) thrombosis is a life-threatening complication occurring in ≈6% of patients receiving a HeartMate II (HMII) LVAD (Thoratec Corp, Pleasanton, CA) within 24 months after implantation. 1 Prophylactic therapy with aspirin and warfarin to an international normalized ratio (INR) of 1.5 to 2.5 is recommended to prevent LVAD thrombosis in most HMII recipients. 2 Fo...

background: antiphospholipid antibodies (apl) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. objective: to study the prevalence of apl in patients with thrombosis at aleppo university hospitals, syria. methods: one hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. anticardiolipin antibodies (...