نتایج جستجو برای: thrombotic microangiopathies
تعداد نتایج: 14502 فیلتر نتایج به سال:
include classical ADAMTS13 deficient acquired (primaryidiopathic) TTP, Shiga toxin-mediated TMA (also called hemolytic-uremic syndrome (HUS)), drug-mediated TMA and complement-mediated TMA (so called atypical HUS). In addition to these, systemic infections, disseminated cancer, severe preeclampsia inc. Hemolysis, Elevated Liver enzymes, and Low Platelets (HELLP) syndrome, malignant hypertension...
The thrombotic microangiopathies (TMAs) and C3 glomerulopathies (C3Gs) include a spectrum of rare diseases such as atypical hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, C3GN, and dense deposit disease, which share phenotypic similarities and underlying genetic commonalities. Variants in several genes contribute to the pathogenesis of these diseases, and identification of thes...
Thanks to their predictable pharmacokinetics and ease of use, low-molecular-weight heparins (LMWHs) have established uses in the prevention and treatment of thrombotic diseases and as a replacement for unfractionated heparin (UFH). Although LMWHs as a class have similar antithrombotic effects, they comprise a diverse group of agents with distinct biochemical and pharmacological profiles. In lig...
Here we report synthesis and characterization of early transition-metal(TM)-substituted decaniobates as a continuation of our previous report of tetramethylammonium (TMA) salt of FeNb9 and NiNb9: TMA6[H2Cr(III)Nb9O28]·14H2O (1, CrNb9), TMA8[Mn(III)Nb9O28]·29H2O (2, MnNb9) and TMA7[H2Co(II)Nb9O28]·25H2O (3, CoNb9). Among the TM-substituted decaniobates, CoNb9 or NiNb9 exhibit a higher photocatal...
We describe the clinical case of two siblings with different presentations of thrombotic phenomena, in which prothrombin mutation was observed.
Thrombotic microangiopathies (TMAs) comprise a group of distinct disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and microvascular thrombosis. For many years distinction between these TMAs, especially between thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), remained purely clinical and hard to make. Recent discoveries shed light on d...
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