نتایج جستجو برای: thyroid hemiagenesis
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Thyroid hemiagenesis (THA) is a rare congenital anomaly. It occurs more frequently in the left lobe and predominantly in women. Most of the cases are asymptomatic. The most frequent associated thyroid disorders with THA are nontoxic nodular goiter and Hashimoto's thyroiditis whereas association of Graves' disease with THA is very rare. We present a man patient with THA and multinodular Graves' ...
Introduction: Thyroid hemiagenesis (THA) is a rare congenital thyroid condition in which one of the lobes gland fails to develop. The etiology remains uncertain, with main hypotheses suggesting genetic alterations embryogenesis associated failure descend its final position. Additionally, may be present both asymptomatic and euthyroid patients, as well those diseases such hyperthyroidism, nodula...
PAX8 gene encodes one of the transcription factors engaged in the regulation of proper development of thyroid gland as well as Müllerian and renal/upper urinary tracts. So far, six alternatively spliced transcripts were reported, however, sequences of only four were deposited in the NCBI database. Here, we evaluate a fragment of a novel variant of PAX8 mRNA formed by an alternative 3' acceptor ...
the classical triad of mccune-albright syndrome (mas) consists of polyostotic fibrous dysplasia (fd), skin hyperpigmentation (café-au-lait spots), and endocrine dysfunction, frequently seen in females as precocious puberty. etiology is genetically based and is explained by mosaicism of activating somatic mutations of the alpha-subunit of gs protein. clinical presentation is varied and is depend...
In this article, we report a very rare case of left thyroid lobe with agenesis, adenomatous hyperplasia and coexisting papillary carcinoma of the right lobe. A 59-year-old asymptomatic woman with no previous thyroid surgery was evaluated sonographically. Ultrasonography and scintigraphy revealed an agenesis in the left lobe and multiple right lobe nodules with one of them diagnosed with papilla...
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