Iodine administered orally as NaI131 associates with two electrophoretically identifiable serum proteins (1-4). It appears first with the albumin fraction where it is associated with the slower moving component. It is later found in a zone of low protein concentration just ahead of alpha-2 globulin. This behavior was observed in the serum from both euthyroid and hyperthyroid subjects. However, ...

We determined appropriate temperatures for sample storage and the resulting stability of 14 analytes commonly radioimmunoassayed in the clinical laboratory. Serum specimens to be tested for concentrations of cholylglycine, cortisol, digoxin, ferritin, follitropin, immunoglobulin E, lutropin, prolactin, thyroxin (also blood-spot thyroxin), triiodothyronine, and triiodothyronine uptake could be s...

The aim of this research was to evaluate the role zinc supplementation on reduction heat stress in local lambs during hot season. In current experiment, twenty-seven were housed indoor individual pens (1.50 × 1.30m). Zinc added fresh drinking water three different levels namely T1 (0 mg Zn/day), T2 (36 Zn/day) and T3 (72 Zn/day). Serum (zinc; µmol/L), Alkaline phosphate (ALP; U/I), Alanine amin...

AIM Primary congenital hypothyroidism is frequently seen endocrine disorder and one of the preventable cause of mental retardation. Aim of study was to evaluate the frequency of permanent/transient hypothyrodism, and to detect underlying reason to identfy any marker which carries potential to discriminate permanent/transient form. MATERIAL AND METHODS Forty eight cases older than 3 years of a...

the goal of this research is to study the effect of benzo-alpha-pyrene (bαp) as a pollutant on the plasma levels of cortisol, thyroxin (t4), and triiodothyronine (t3) hormones, and the t3/t4 ratio in the yellowfin sea bream, acanthopagrus latus. the bαp (50 mg kg-1) in vegetable oil was peritoneally injected. blood samples were obtained from the treated and control groups after 3 and 72 hr, res...

Formaldehyde (HCHO) exposure in industry causes health impairment, especially immune profile. Male albino rats when exposed to HCHO at 5, 10, 15 mg/kg day for 30 days showed decrease in thyroid weight in 10, 15 mg/kg/day HCHO fed group with commensurate follicular regression (epithelial cells), decreased triiodothyronine (T3), thyroxin (T4) deficiency and enhanced thyroid stimulating hormone (T...

We describe a one-step, labeled-antibody radioassay for measuring free thyroxin (FT4) in serum or plasma, based on a novel principle. FT4 in the sample competes with a gross molar excess (over antibody) of a cross-reactant (L-triiodothyronine, T3), chemically coupled to magnetizable polymer particles, for binding to avid 125l-labeled monoclonal anti-thyroxin antibodies. As in conventional immun...

We compared the utility of a sensitive immunoradiometric assay for serum thyrotropin as a "first-line" thyroid-function test with a strategy based on first measuring total thyroxin in serum. The immunoradiometric assay appears to distinguish primary hypothyroidism and hyperthyroidism from euthyroidism in "new" patients. The role of this test in monitoring antithyroid treatment or thyroxin-repla...