Pathologists use loss of normal tissue architecture as a key criterion to identify and categorize disease states. Epithelia in all glandular structures in vivo have a characteristic organization where they line a central lumen and are involved in absorptive and/or secretory functions. Under some physiological conditions— such as pregnancy, wound healing, and the periodic tissue remodeling that ...

Recently reported contrast in phase images of human and animal brains obtained with gradient-recalled echo MRI holds great promise for the in vivo study of biological tissue structure with substantially improved resolution. Herein we investigate the origins of this contrast and demonstrate that it depends on the tissue "magnetic architecture" at the subcellular and cellular levels. This archite...

this article presents a novel method and development paradigm that proposes a general template for an enterprise information structure and allows for the automatic generation and modification of enterprise workflows. this dynamically integrated workflow development approach utilises a conceptual ontology of domain processes and tasks, enterprise charts, and enterprise entities. it also suggests...

ABSTRACT The second EMBO-EMBL Symposium ‘Synthetic Morphogenesis: From Gene Circuits to Tissue Architecture’ was held virtually in March 2021, with participants from all over the world joining comfort of their sofas discuss synthetic morphogenesis at large. Leading scientists a range disciplines, including developmental biology, physics, chemistry and computer science, covered gamut topics prin...

Introduction: Brain tumors such as glioma are among the most aggressive lesions, which result in a very short life expectancy in patients. Image segmentation is highly essential in medical image analysis with applications, particularly in clinical practices to treat brain tumors. Accurate segmentation of magnetic resonance data is crucial for diagnostic purposes, planning surgical treatments, a...