نتایج جستجو برای: tlr ii
تعداد نتایج: 587899 فیلتر نتایج به سال:
The four Toll/IL-1R domain-containing adaptor proteins MyD88, MAL, TRIF, and TRAM are well established as essential mediators of TLR signaling and gene induction following microbial detection. In contrast, the function of the fifth, most evolutionarily conserved Toll/IL-1R adaptor, sterile α and HEAT/Armadillo motif-containing protein (SARM), has remained more elusive. Recent studies of Sarm(-/...
background: toll like receptors (tlrs) are one of the main components of the innate immune system. it has been reported that expression of these receptors are altered in the female reproductive tract (frt) during menstrual cycle. here we used a fallopian tube epithelial cell line (oe-e6/e7) to evaluate the effect of two sex hormones in modulating tlr expression. materials and methods: in this e...
AIM To analyze the effect of TLR-9 (-1486 T>C) and TLR-9 (C>T) gene polymorphisms both at TLR-9 levels and together with their sepsis parameters. In this regard, the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique was used in order to detect TLR-9 gene polymorphisms, whereas the ELISA technique was used to analyze TLR-9 serum levels in 80 sepsis patients ...
INTRODUCTION Toll-like receptors (TLRs) are an important link between innate and adaptive immunity. MATERIAL AND METHODS Expression of TLR-2, TLR-4, and TLR-9 genes was assessed in 60 coronary artery disease (CAD) patients and 79 controls by SYBR Green 1 based real time PCR assay. RESULTS Expression of the TLR-2 gene was found to be significantly elevated in cases (1.295 ±0.09) compared to ...
Angiographic patterns of in-stent restenosis: classification and implications for long-term outcome.
BACKGROUND The angiographic presentation of in-stent restenosis (ISR) may convey prognostic information on subsequent target vessel revascularizations (TLR). METHODS AND RESULTS We developed an angiographic classification of ISR according to the geographic distribution of intimal hyperplasia in reference to the implanted stent. Pattern I includes focal (< or =10 mm in length) lesions, pattern...
Dendritic cells (DC) are multi-functional cells that bridge the gap between innate and adaptive immune systems. In bovine, significant information is lacking on the precise identity and role of peripheral blood DC subsets. In this study, we identify and characterize bovine peripheral blood DC subsets directly ex vivo, without further in vitro manipulation. Multi-color flow cytometric analysis r...
PURPOSE Positron emission tomography (PET) with (18)F-fluorodeoxyglucose (FDG) has been widely used in the management of colorectal cancer (CRC). However, the relationship between FDG accumulation and KRAS/BRAF mutations has not yet been investigated. The purpose of this study was to investigate whether KRAS/BRAF mutations affect FDG accumulation in CRC. EXPERIMENTAL DESIGN Retrospective anal...
BACKGROUND AND OBJECTIVES Triple anti-platelet therapy is known to prevent restenosis after drug-eluting stent (DES) implantation. However, there is little available data concerning the efficacy of triple anti-platelet therapy for acute myocardial infarction (AMI). SUBJECTS AND METHODS We analyzed 528 consecutive patients with AMI undergoing DES implantation between Nov 2005 and Apr 2008. We ...
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