In the United States, sexually transmitted diseases due to Chlamydia trachomatis and Neisseria gonorrhoeae continue to be a major public health burden. Screening of extragenital sites including the oropharynx and rectum is an emerging practice based on recent studies highlighting the prevalence of infection at these sites. We reviewed studies reporting the prevalence of extragenital infections ...

Epstein-Barr is a ubiquitous virus that infects 95% of the world population at some point in life. Although Epstein-Barr virus (EBV) infections are often asymptomatic, some patients present with the clinical syndrome of infectious mononucleosis (IM). The syndrome most commonly occurs between 15 and 24 years of age. It should be suspected in patients presenting with sore throat, fever, tonsillar...

Abstract Background Nasopharyngeal stenosis (NPS) is a rare condition defined as the obstruction of communication between oropharynx and nasopharynx owing to scar contracture soft palate, tonsillar pillars, posterior pharyngeal wall. NPS could be primary (attributed disease process such rhinoscleroma) or secondary caused by prior surgery. In this study, we discuss clinical manifestation acquire...

Regulatory T cells (Tregs) play a critical role in immune regulation and peripheral tolerance. While different types of Tregs have been identified both mice humans, much our understanding about how these maintain homeostasis is derived from animal models. In this study, we examined two distinct human lymphoid organs to understand repeated exposure infections at the mucosal surface influences ph...

OBJECTIVES This study aimed to characterise the epidemiology of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) and transgender women (TW) in Lima, Peru. SETTING Cross-sectional study in Lima, Peru. PARTICIPANTS We recruited a group of 510 MSM and 208 TW for a subsequent community-based randomised controlled trial. The presence of C...

The palatine tonsils, localized in the oropharynx, are easily accessible secondary lymphoid tissue in humans. Inflammation of the palatine tonsils, local and chronic in case of chronic tonsillitis (CT) or acute in the presence of a peritonsillar abscess (PTA), ranks among the most common diseases in otolaryngology. However, the functionality of tonsillar immune cells, notably T-cells, in the co...

OBJECTIVE To investigate, by use of the Amplicor PCR in a routine setting, the recovery rate of Chlamydia trachomatis in ano-rectal and pharyngeal swab samples obtained from males and females attending an STD clinic in relation to sexual practices, symptoms, and signs. DESIGN Data regarding sexual practices, and symptoms and signs related to the rectum and pharynx, were obtained from 196 fema...

BACKGROUND Adenovirus is one of the most common causes of viral acute respiratory infections. To identify the types of human adenoviruses (HAdVs) causing respiratory illness in Beijing, a sentinel surveillance project on the viral aetiology of acute respiratory infection was initiated in 2011. PRINCIPAL FINDINGS Through the surveillance project, 4617 cases of respiratory infections were ident...

human metapneumovirus (hmpv) infection plays an important role in the pediatric respiratory infections. the aim of this study was to determine the relationship between asthma and wheezing with hmpv in hospitalized children. nasal pharyngeal swabs obtained from 120 children aged 1-60 months, hospitalized during a one year period, were tested for the hmpv by rt-pcr. hmpv was detected in 20 (16.6%...

Hamartomas are disorganized but benign masses composed of cells indigenous to the involved site. They have been reported in almost all organs but are rare in the head and neck region, especially the pharynx. We describe the case of a six-month-old male infant who presented with acute respiratory symptoms due to a pedunculated polypoid mass arising from his left palatine tonsil. He underwent a t...