objective: basic fibroblast growth factor (bfgf) is a cytokine involved in angiogenesis, tissue remodeling and stimulation of osteoblasts and osteoclasts. the present study assesses the effects of a local injection of bfgf on the rate of orthodontic tooth movement. materials and methods: in this laboratory animal study, we randomly divided 50 rats into 5 groups of 10 rats each. rats received 0....

Mechanical force loading exerts important effects on the skeleton by controlling bone mass and strength. Several in vivo experimental models evaluating the effects of mechanical loading on bone metabolism have been reported. Orthodontic tooth movement is a useful model for understanding the mechanism of bone remodeling induced by mechanical loading. In a mouse model of orthodontic tooth movemen...

It has previously been reported that low-energy laser irradiation stimulated the velocity of tooth movement via the receptor activator of nuclear factor kappa B (RANK)/RANK ligand and the macrophage colony-stimulating factor/its receptor (c-Fms) systems. Matrix metalloproteinase (MMP)-9, cathepsin K, and alpha(v) beta(3) [alpha(v)beta3] integrin are essential for osteoclastogenesis; therefore, ...

The porpose of this study was to determine the optimal length of power arms for achieving controlled anterior tooth movement in segmented arch mechanics combined with power arm. A three-dimensional finite element method was applied for the simulation of en masse anterior tooth retraction in segmented power arm mechanics. The type of tooth movement, namely, the location of center of rotation of ...

Objective(s): to determine the effect of different doses of caffeine on orthodontic tooth movement (OTM) in rats. Materials and Methods: Forty male 250-300 g Sprague-Dawley rats were randomly divided into four groups of ten animals each and received 0 (control), 1 g/l, 2 g/l and 3 g/l caffeine in tap water for 3 days. Orthodontic appliances were ligated between the maxillary first molars and in...

The purpose of this study was to develop a new finite element method for simulating long-term tooth movements and to compare the movement process occurring in canine retraction using a T-loop spring having large bends and with that having small bends. Orthodontic tooth movement was assumed to occur in the same manner as the initial tooth movement, which was controlled by the moment-to-force (M/...

The finite element method is a useful technique for measuring structural stress and for movement analyses. The objective of this investigation was to get a more accurate estimation of tooth movement depending on application point when a tipping orthodontic force is applied. The three-dimensional model of un upper canine, consisting of 4,000 hexahedron elements with 2,367 nodes was obtained. Hor...