conclusions although the results of this study showed superiority of application of emla cream as a topical anesthetic for pain relief of blood sampling, both lidocaine 5% and benzocaine 5% offer considerable efficacy in pain relief of venipuncture. results at the end of study, the emla products (a and b) caused a significant decrease in pain (p < 0.05) in comparison with the products c (lidoca...

in order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. the commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. the release of therapeutic agents in vitro from medicated sp...

A modified assimilable organic carbon (AOC) bioassay is proposed. We evaluated all aspects of the AOC bioassay technique, including inoculum, incubation water, bioassay vessel, and enumeration technique. Other concerns included eliminating the need to prepare organic carbon-free glassware and minimizing the risks of bacterial and organic carbon contamination. Borosilicate vials (40 ml) with Tef...

Nine refinery streams were tested in both chronic and initiation/promotion (I/P) skin bioassays. In the chronic bioassay, groups of 50 C3H/HeJ mice received twice weekly applications of 50 microl of test article for at least 2 years. In the initiation phase of the I/P bioassay, groups of CD-1 mice received an initiating dose of 50 microl of test article for 5 consecutive days, followed by promo...

Context: Medicinal plants contains some pesticidal activities that may control stored product insects. Objectives: To elucidate the insecticidal activity from the stem bark extracts of nishinda (Vitex negundo L.) and their toxicity against red flour beetle, Tribolium castaneum (Herbst) (Tenebrionidae). Materials and Methods: The powdered stem bark (250 g) was extracted with methanol (MeOH), eth...

A modified version of a simplified in vivo test was applied to assess the susceptibility of Plasmodium falciparum to chloroquine among semi-immune febrile children in Kouroussa, Guinea. In 27% of cases, a partial response (RI/RII) to chloroquine was observed; the remainder showed a good response (S/RI). This test is both practical and useful to assess the efficacy of chloroquine at the intermed...

Abstract Background Topical application of the entomopathogenic fungi (EPFs) against Spodoptera frugiperda J.E. Smith (Lepidoptera: Noctuidae) larvae is less effective due to hiding in corn midribs field. To control larvae, colonize plant tissues or endophytic are needed. There no information on pathogenicity from Indonesia development S. . The isolated infected-host cadavers South Sumatra (Ind...