The purpose of this study was to compare root-end sealing using 4-META/MMA-TBB resin with that using conventional retrograde root filling technique, and thereby determine if 4-META/MMA-TBB resin offers long-term prevention against dye leakage from the root canal of human teeth. Thirty-five teeth had the apical 2.5 mm of the root resected. In the Sealing (SB) group, 4-META/MMA-TBB resin was appl...

Long-term survival of lung transplant recipients is limited by the advent of obliterative bronchiolitis and irreversible airways obstruction, e.g. bronchiolitis obliterans syndrome (BOS). This study investigated whether inflammatory cells and their activation markers were increased in bronchoalveolar lavage (BAL) and transbronchial biopsies (TBB) from patients with BOS. Levels of antioxidants i...

Transbronchial biopsy using forceps (TBB) is the first diagnostic technique performed on patients with interstitial lung disease (ILD). However, the small size of the samples and the presence of artefacts in the tissue obtained make the yield variable. Our objectives were 1) to attempt to reproduce transbronchial cryobiopsy under the same conditions with which we performed conventional TBB, tha...

A buffer is defined as a compound that in small concentrations can impart a resistance to large pH changes. Common buffers contain two substances, a conjugate base and a conjugate acid. There are acidic buffers that contain a weak acid and the salt of a weak acid (the conjugate base) and basic buffers that contain a weak base and the salt of a weak base (the conjugate acid). The combination of ...

Casein kinase 2 (CK2) is a highly conserved, ubiquitously expressed serine/threonine protein kinase with hundreds of substrates. The role of CK2 in the G2/M transition of oocytes, zygotes, and 2-cell embryos was studied in mouse by enzyme activity inhibition using the specific inhibitor 4, 5, 6, 7-tetrabromobenzotriazole (TBB). Zygotes and 2-cell embryos were arrested at G2 phase by TBB treatme...

The aim of this study was to assess the usefulness of endobronchial ultrasound transbronchial biopsy with guide-sheath (EBUS-GS-TBB) for the diagnosis of solitary pulmonary nodules (SPNs). One hundred and eighty patients, who were diagnosed with SPNs and underwent an endobronchial ultrasound procedure. The diagnostic yield, safety and the associated factors were analyzed. Mean EBUS-GS procedure...

4-META/MMA-TBB resin has shown good biocompatibility and remarkable adhesion to dentin. It seems to be suitable for use in periodontal tissues for retrograde root sealing and treatment of vertically fractured roots. For an adhesive resin to be useful clinically, it must bond not only to the dentin but also to the cementum. The purpose of this study was to evaluate the long-term adhesion durabil...

Recently, there has been renewed interest in the importance of the small airways (internal perimeter v6 mm) in asthma [1]. This was initiated largely by the observation that the use of the inhaled corticosteroid beclomethasone as a small-particle formulation, with greater penetration to the peripheral lung, results in similar improvements in symptoms and lung function at half the delivered dose...

Based on ten-year tropical cyclones (TCs) observations from 2009 to 2018, the black body temperature (TBB, also called cloud-top brightness temperature) data obtained infrared channel 1 (with wavelength of 10.30–11.30 µm) FY-2 satellite image, and wind observation at automatic weather stations (AWSs) in Guangdong province, this study explores relationship between TBBs winds induced by TCs AWSs....

BACKGROUND The protein kinase CK2 sustains multiple pro-survival functions in cellular DNA damage response and its level is tightly regulated in normal cells but elevated in cancers. Because CK2 is thus considered as potential therapeutic target, DNA double-strand break (DSB) formation and rejoining, apoptosis induction and clonogenic survival was assessed in irradiated mammalian cells upon che...