Background The Monitored Atherosclerosis Regression Study, a randomized, double-blind, placebo-controlled, 2-year trial of lovastatin monotherapy, found that coronary lesions <50% diameter stenosis (%S) and coronary lesions .50%S at baseline had different responses to therapy. We now report on clinical, lipid, and nonlipid risk factors of treatment response in these lesion subsets. Methods and ...

Background and Objectives: Capparis decidua is a plant used in herbal medicine. This study was carried out to assess effects of C. decidua hydroalcoholic extract on blood glucose, lipid profile and leptin in male rats with high-cholesterol diets. Materials and Methods: Totally, 40 Wistar-albino male rats with 200–250 g weight were equally divided into one control (C) and three experimental gro...

RESEARCH DESIGN AND METHODSdEligible Japanese men and women (1,771) aged 40–70 years with type 2 diabetes from 59 institutes nationwide were followed for a planned 8-year period. The performance of eight conventional lipid variables, i.e., total cholesterol (TC), LDL-cholesterol (LDLC), HDL-cholesterol (HDLC), triglycerides (TGs), non-HDLC, TC/HDLC ratio, LDLC/HDLC ratio, and TG/HDLC ratio, as ...

PURPOSE Pancreatic carcinoma is a malignant tumor with poor prognosis. This metaanalysis was conducted to investigate if there exists any association of cholesterol with pancreatic carcinoma risk. METHODS A literature search was performed in Cochrane Central Library, PubMed, MEDLINE, EMBASE, CNKI (China National Knowledge Infrastructure), China Biology Medical literature database (CBM), and W...

BACKGROUND Animal studies have demonstrated that an inhibition of DPP-4 has an impact on the secretion of cholesterol and apoB by the small intestine. However, there is no consensus about the changes of the lipid profile following administration of sitagliptin. METHODS Accordingly, we treated patients who had type 2 diabetes complicated by dyslipidemia with sitagliptin and evaluated its effec...

Overweight and obesity are increasing problems in many countries and are related to multiple cardiovascular risk factors. Although imaging techniques can determine total body fat and its distribution reliably, anthropometric measurements remain important in clinical practice. The purpose of this study was to determine the association between some anthropometric measurements and dyslipidemia as ...

conclusions there was no difference between the effects of 2 g of epa or dha supplementation for 12 weeks on the levels of total cholesterol, ldl-c, hdl-c, tc/hdl-c, tg/hdl-c, and ldl-c/hdl-c; however, it had a desirable effect on the level of tg in a way that the effect of dha was clearer. results from 105 included patients, 97 (31 in epa, 33 in dha, and 33 in control groups) completed the stu...

OBJECTIVE To evaluate the test performance of specific body mass index (BMI) percentile cutoffs for detecting children/adolescents with hypercholesterolemia. DESIGN Cross-sectional analysis. SETTING National Health and Nutrition Examination Survey 1999-2004. PARTICIPANTS Population-based sample of children (aged 3-18 years) with nonfasting total cholesterol (TC) and high-density lipoprote...

So far, no studies have been conducted to evaluate possible correlations between lipid/lipoprotein levels and the anti-phospholipid antibody (aPL) positivity in multiple sclerosis (MS). In this cross-sectional study, we aimed to investigate the relationships between serum lipid profile and aPL positivity rates in MS patients, and their possible differences among secondary-progressive MS (SPMS) ...

Experimental studies have reported that common antihypertensive drugs such as diuretics, beta-blockers, and methyldopa have adverse effects on plasma lipids and lipoproteins. To investigate whether such effects can be observed in the general population, plasma lipid and lipoprotein levels were compared in subjects receiving antihypertensive treatment, subjects with untreated high blood pressure...