PURPOSE To determine the metabolically active whole-body tumor volume (WB-MTV) on F-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) in individuals with neurofibromatosis type 1 (NF1) using a three-dimensional (3D) segmentation and computerized volumetry technique, and to compare PET WB-MTV between patients with benign and malignant peripheral nerve sheat...

Materials and Methods: Institutional review board approved retrospective study identified patients diagnosed with Stage 3B NSCLC (8 edition TNM classification) on baseline FDG PET/CT at two medical centers (Medical centers A and B), between Feb 2004 and Dec 2014. Patients were excluded if they had prior NSCLC treatment or recent diagnosis of a second primary cancer. Quantitative FDG PET/CT para...

The aim of this study was to compare several threshold-based segmentation methods in delineating tumours on preand posttherapy PET scans both in terms of the volumes segmented and the effect on predicting survival. On a dataset of 14 patients with mesothelioma, different segmentation methods were found to correlate well with each other for preand posttherapy tumour volume (TV) and total lesion ...

Accurate prediction of cancer prognosis before the start of treatment is important since these predictions often affect the choice of treatment. Prognosis is usually based on anatomical staging and other clinical factors. However, the conventional system is not sufficient to accurately and reliably determine prognosis. Metabolic parameters measured by (18)F-fluorodeoxyglucose (FDG) positron emi...

Accurate prognosis in patients with lung cancer is important for clinical decision making and treatment selection. The TNM staging system is currently the main method for establishing prognosis. Using this system, patients are grouped into one of four stages based on primary tumor extent, nodal disease, and distant metastases. However, each stage represents a range of disease extent and may not...

Introduction. This study aimed to examine the efficacy of positron emission tomography in fusion with computed (PET-CT) parameters predicting survival outcomes for patients malignant pleural mesothelioma. Material and methods. retrospectively evaluated data 250 who were followed up after a diagnosis The relationship pre-treatment [maximum standardized uptake value (SUVmax1), metabolic tumor vol...

To assess the capability of fractional water content (FWC) texture analysis (TA) to generate biologically relevant information from routine PET/MRI acquisitions for colorectal cancer (CRC) patients. Thirty consecutive primary CRC patients (mean age 63.9, range 42–83 years) prospectively underwent FDG-PET/MRI. FWC tumor parametric images generated Dixon MR sequences TA using commercially availab...