Several lines of evidence suggest that oxidatively modified low density lipoprotein (LDL) is atherogenic and that antioxidants may protect LDL against oxidation. In addition, cigarette smoking is known to induce oxidant stress. We have examined the effect of ingestion of the antioxidants D,L-alpha-tocopherol (vitamin E) and beta-carotene and of smoking on the resistance of LDL against copper-me...

Several lines of evidence suggest that oxidatively modified low density lipoprotein (LDL) is atherogenic and that antioxidants may protect LDL against oxidation. In addition, cigarette smoking is known to induce oxidant stress. We have examined the effect of ingestion of the antioxidants D,L-ar-tocopherol (vitamin E) and 0-carotene and of smoking on the resistance of LDL against copper-mediated...

Vitamin E is an essential nutrient for human health, with an established function as a lipid-soluble antioxidant that protects cell membranes from free radical damage. Low vitamin E status has been linked to multiple health outcomes, including total mortality. With vitamin E being identified as a 'shortfall nutrient' because >90% of American adults are not consuming recommended amounts of vitam...

Several studies in macrophage cell lines, rodent macrophages, and animal models of atherosclerosis suggest that vitamin E may prevent the formation of foam cells. We tested this hypothesis in a recently developed, fully autologous in vitro model of human foam cell formation. During maturation, macrophages continuously increased their a-tocopherol/total cholesterol ratio, demonstrating that thes...

Several studies in macrophage cell lines, rodent macrophages, and animal models of atherosclerosis suggest that vitamin E may prevent the formation of foam cells. We tested this hypothesis in a recently developed, fully autologous in vitro model of human foam cell formation. During maturation, macrophages continuously increased their alpha-tocopherol/total cholesterol ratio, demonstrating that ...

This study evaluates the effect of two contrasting years, in terms climatic parameters, on kernel morphology and content composition oil, tocopherols 11 macro- micro-elements almonds. Low precipitation high temperatures increased tocopherols, Cu Zn but decreased ratio, oil content, levels macro-elements Cr, Fe, Mn Mo. The obtained data indicate some statistically significant correlations among ...

Plasma vitamin E values of newborn infants in a Coloured population of Cape Town have been determined. The mean plasma alpha-tocopherol value was 3,2 +/- 0,8 mg/l. A significant correlation between the plasma alpha-tocopherol level and plasma total lipid content (r = 0,45; P less than 0,001) and plasma cholesterol level (r = 0,65; P less than 0,001) has been found. However, maternal and neonata...

PURPOSE To assess the alpha-tocopherol concentration in the serum and colostrum of adolescent and adult mothers and to determine the nutritional adequacy of vitamin E in the colostrum offered to infants. METHODS In total, 72 pregnant women participated in the study, 25 adolescents and 47 adults. An amount of 5 mL of blood and 2 mL of colostrum were collected under fasting conditions for the a...

The oil contents of linseeds were determined between 39.9% (Antares) and 43.3%  (Railinus). The oleic acid contents of seed oils varied between 0.8% (Maroc) and 24.8 (Railinus). The linoleic acid contents of linseed oil change between 10.2% (Avangard) and 48.2% (Maroc), while the palmitic acid of oils ranged from 4.8% (Antares) to 6.1% (Maroc), stearic acid contents ranged between 4.7% (Ava...

According to the free radical theory by Harman, free radicals formed under various conditiors can cause the changes in DNA, which may result in chromosomal aberrations, and can initiate lipid peroxidation in subcellular and cellular membrane systems. The accumulation cf lipofuscin with age .also supports the significance of lipid peroxidation on aging. In this paper·;two lines of research were ...