We present a case of hepatocellular carcinoma (HCC), showing an atypical "nodule-in-nodule" appearance on ultrasonogram (US). In general, a "nodule-in-nodule" appearance is found as a hyperechoic tumor containing a hypoechoic nodule. In the present case, however, there was a hyperechoic subnodule in the center of the tumor, which was surrounded by a hypoechoic tumor area. Histologically, the su...

Metastatic cancer of the umbilicus, known as Sister Mary Joseph nodule, is typically associated with visceral malignancy. It is an uncommon and rare presentation. It indicates disseminated disease and poor prognosis. Physicians need to be aware of this rare clinical condition so that they can promptly diagnose the primary cancer.

PURPOSE To determine the prevalence, clinical characteristics and nature of subfoveal nodules in Coats' disease and the associated impact on the long-term visual outcome. METHODS Consecutive cases of Coats' disease with foveal exudation were retrospectively reviewed. The presence of a subfoveal nodule or macular fibrosis was recorded. Clinical characteristics, retinal imaging, and outcome wer...

background: sonoelastography is a new ultrasound method which could be helpful to determine which thyroid nodule is malignant. we designed this study to evaluate the accuracy of sonoelastography in differentiating of benign and malignant thyroid nodules in iranian patients. methods: forty thyroid nodules in forty consecutive patients who had been referred for sonography‑guided fine‑needle aspir...

377 patients with single thyroid nodule who clinically were candidates for surgery, were selected from the patients that referred to the clinics of endocrinology at namazee hospital, shiraz medical school. fine needle aspiration (fna) was carried out without performing thyroid scan and the results were compared with histology obtained by surgery to establish its accuracy in our center. which is...

introduction: a thyroid nodule is a palpable swelling in a thyroid gland with an otherwise normal appearance. palpable thyroid nodules occur in 4 to 7 percent of the population. nodular thyroid diseases are more frequent in women than in men. most actions of thyroid hormone are mediated by the active form of thyroid hormone. d2 is essential for formation of active hormone of t3 through deiodina...

abstract bronchoalveolar carcinoma presenting as non-resolving consolidation is an uncommon presentation. the typical presentation of bronchoalveolar carcinoma is asymptomatic (solitary nodule) and remains without symptoms even as disease disseminates. we report a case of bronchoalveolar carcinoma presenting as non-resolving consolidation in a young male with productive cough, exertional breath...

introduction acute lymphoblastic leukemia (all) is the most common malignancy of childhood. patients with all commonly present with easy bruising and infections due to medullary involvement. the extra medullary involvements of all manifests as hepatosplenomegaly, lymphadenopathy, and testicular enlargement. among extramedullary manifestations of the all, thyroid involvement is rare. herein, we ...

background transient hypocalcemia is one of the postoperative complications of thyroidectomy for thyroid nodules, and intraoperative and postoperative intact parathyroid hormone (ipth) assays are used to predict postoperative hypocalcemia. objectives the current study was conducted to evaluate a single serum ipth measurement on postoperative day 1 (pod 1) as a means to predict hypocalcemia occu...

Legume root nodules are induced by N-fixing rhizobium bacteria that are hosted in an intracellular manner. These nodules are formed by reprogramming differentiated root cells. The model legumeMedicago truncatula forms indeterminate nodules with a meristem at their apex. This organ grows by the activity of the meristem that adds cells to the different nodule tissues. In Medicago sativa it has be...