BACKGROUND Polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins, and poly-chlorinated dibenzofurans adversely affect the health of humans and various animals. Such effects might be partially exerted through the thyroid hormone (TH) system. We previously reported that one of the hydroxylated PCB congeners suppresses TH receptor (TR)-mediated transcription by dissociating TR from t...

BACKGROUND While some studies indicate that permanent pacemaker implantation is associated with development of tricuspid regurgitation (TR), other studies indicate no association.Little is known about the impact of temporary lead insertion during ablation procedures, or whether therapy (CRT) prevents TR post-device implantation. HYPOTHESIS We hypothesized that permanent, but nottemporary endo...

Although the role of the three functional thyroid hormone receptor isoforms (TR beta 1, TR beta 2, and TR alpha 1) remains unclear, studies by Hodin and Lazar et al. have suggested that restriction of TR beta 2 messenger RNA (mRNA) to rat pituitary could reflect a specific regulatory role in the pituitary. Supporting their hypothesis was a significant fall in pituitary TR beta 2 mRNA after T3 a...

Tone Reservation (TR) is one of the well-known methods for PAPR reduction of Orthogonal Frequency Division Multiplexing (OFDM) systems. In this method some sub-carriers are reserved for PAPR reduction and the symbols in these sub-carriers are selected such that the PAPR of the OFDM frame is minimized. In this paper, the iterative algorithm introduced earlier for TR method in single antenna OFDM...

Here we studied ability of two naphthoquinones to inhibit Leishmania growth (2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone (TR 001) and 2,3-dibromo-1,4-naphthoquinone (TR 002). TR 001 was more efficient than TR 002 in inducing killing of promastigotes and intracellular amastigotes. These values compare well to those obtained with the standard first-line antileishmanial agent sodium stiboglucona...

Let Fn,tr(n) denote the family of all graphs on n vertices and tr(n) edges, where tr(n) is the number of edges in the Turán’s graph Tr(n) – the complete r-partite graph on n vertices with partition sizes as equal as possible. For a graph G and a positive integer λ, let PG(λ) denote the number of proper vertex colorings of G with at most λ colors, and let f(n, tr(n), λ) = max{PG(λ) : G ∈ Fn,tr(n...

Time reversal (TR) can achieve temporal and spatial focusing by exploiting diversity in complex underwater environments with significant multipath. This property makes TR useful for acoustic (UWA) communications. Conventional is realized performing equal gain combining (EGC) on the single element output signals of each vertical receive array (VRA). However, actual environment, signal-to-noise r...

The effects of thyroid hormones on metabolism and development are mediated by thyroid hormone receptors (TRs). We report the cloning and characterization of a TR beta1 cDNA from zebrafish. Southern blot analysis revealed that there is a single genomic locus for the TR beta gene, while the TR alpha gene potentially has two loci. Multiple TR alpha and TR beta transcripts were detected in adult ti...

Mammalian thioredoxin reductase (TR) is a flavoprotein catalysing reduction of oxidized thioredoxin in an NADPH-dependent manner, and contains a selenocysteine (Sec) residue near the C-terminus. We observed that TR activity was decreased in A549 cells by the lowering of the fetal bovine serum content in the culture medium and was recovered by the addition of selenium. To study the role of Sec i...