The investment in small hydropower plants requires the analysis of hydrological, technical, operational, budgetary, economical and financial aspects. The analysis of each possible configuration demands the joint action of several technicians, consuming substantial time and money. During initial design of the project, simplified procedures are usually adopted which may compromise the quality of ...

In this work we apply the FDA proposed precision criteria necessary for pediatric pharmacokinetic studies (Wang et. al., 2012) as a stopping criteria for a model based adaptive optimal design (MBAOD) of an adult to children pharmacokinetic bridging study. We demonstrate the power of the MBAOD compared to both traditional designs as well as non-adaptive optimal designs.

Traffic engineering on a given network is the task of determining how traffic commodities must be routed in order to maintain an optimal performance. In this work, we aim to optimize routing by minimizing the number of routing hops, which has a positive impact on the delay provided by the network to traffic commodities, while ensuring some desired survivability guarantees. In [1], we have consi...

In this paper, we consider the minimization of a relevant energy consumption related cost function in the context of sensor networks where correlated sources are generated at various sets of source nodes and have to be transmitted to some set of sink nodes. The cost function we consider is given by the product [rate] × [link weight]. The minimization is achieved by jointly optimizing the transm...