This research studied the viability of probiotic bacterium Lactobacillus plantarum (L. plantarum) encapsulated in internal aqueous phase (W1) a water-in-oil-in-water (W1/O/W2) emulsion system, with help gelation and different gelling agents. Additionally, physicochemical, rheological, microstructural properties fabricated systems were assessed over time under effect W1 gelation. The average dro...

Nanoparticles or microparticles created by physical complexation between two polyelectrolytes may have a prospective use as an excipient for oral insulin administration. Natural polymers such as tragacanth, alginate, dextran, pullulan, hyaluronic acid, gelatin and chitosan can be potential candidates for this purpose. In this research, insulin particles were prepared by the inclusion of insulin...

Article history: Received on: 23/05/2013 Revised on: 05/07/2013 Accepted on: 01/09/2013 Available online: 30/09/2013 The main objective of the present work was to develop sustained release matrix tablets of Atenolol. To reduce the frequency of administration and to improve the patient compliance, a once daily sustained release formulation of Atenolol is desirable. So sustained release Matrix Ta...

Some excipients are currently available for the formulation of Pharmaceutical suspensions. The purpose of this study is to search for a cheap and effective natural excipient that can be used as an effective alternative for the formulation of pharmaceutical suspensions. The mucilage from the pods of Abelmoschus esculentus was subjected to preformulation study for evaluation of its safety and sui...

Introduction: Gum Tragacanth (GT) obtained from Astragalus gossypinus is one of the most widely used natural gums which has found applications in many areas because of its attractive features such as biodegradability, nontoxic nature, natural availability, moisture absorption and creating a network of Hydrocolloid. It also has properties like maintenance and delivery of drugs, higher resistance...

The stability of type 2 dengue virus to exposure to a variety of laboratory conditions was determined. Suckling mouse brain passage virus was adapted for growth in BHK-21 cells, and plaque assays were performed using a tragacanth gum overlay. A three- to fourfold increase in plaque size could be obtained if monolayers were subconfluent at time of inoculation. Incubation of virus for 24 h at 37 ...