BACKGROUND Noise is defined as a sound or series of sounds that are considered to be invasive, irritating, objectionable and disruptive to the quality of daily life. Noise is one of the environmental pollutants, and in cities it is usually originated from road traffic, railway traffic, airports, industry etc. The tram is generally considered as environmentally friendly, namely non-polluting and...

OBJECTIVES The aim of this study is the evaluation of the influence of repeated (5 times for 15 min) exposure to electromagnetic field (EMF) of 1800 MHz frequency on tissue lipid peroxidation (LPO) both in normal and inflammatory state, combined with analgesic treatment. MATERIAL AND METHODS The concentration of malondialdehyde (MDA) as the end-product of the lipid peroxidation (LPO) was esti...

The introduction of microsurgery has decreased the frequency of using the pedicled transverse rectus abdominis musculocutaneous (TRAM) flap, owing to its higher incidence of fat necrosis and limitations in flap insetting (vs. the free TRAM flap). We devised an efficient method of using zones 2 and 4, based on the pedicled flap's vascular anatomy, to reduce fat necrosis and achieve superior aest...

Toll–IL-1–resistance (TIR) domain–containing adaptor-inducing IFN(TRIF)–related adaptor molecule (TRAM) is the fourth TIR domain–containing adaptor protein to be described that participates in Toll receptor signaling. Like TRIF, TRAM activates interferon regulatory factor (IRF)-3, IRF-7, and NFB-dependent signaling pathways. Toll-like receptor (TLR)3 and 4 activate these pathways to induce IFN/...

BRT appears to be less expensive to build and operate than tram systems but can it really approach the performance level of a tram system and what is the environmental performance of comparable systems? This paper reports systematic research on these issues, particularly relating to where an urban transit system seeks to attract discretionary car users. A model has been developed to compare the...

PURPOSE To perform a retrospective cohort study to determine the rates of recall and cancer detection and then to develop a decision analytic model to evaluate the effectiveness of routine screening of transverse rectus abdominis myocutaneous (TRAM) flap reconstructions. MATERIALS AND METHODS This study was approved by the institutional review board, and the methods comply with HIPAA regulati...

Our previous studies demonstrated that HSV-2 infection up-regulates TLR4 expression and induces NF-kB activity, thereby facilitating innate immune response in human cervical epithelial cells. This process requires involvement of TLR4 adaptors, Mal and MyD88. In the current study, we found that HSV-2 infection increases levels of phosphoryalted IRF3 and IRF7, then regulating expression of type I...

closure of fascia after transverse rectus abdominis musculocutaneous (tram) flap has usually been performed with direct closure or synthetic material. the dermal autograft was removed from zone iv of flap was an alternative to reinforce fascial closure. the dermal autograft was used in 34 patients after tram harvest for breast, head and neck reconstruction and prolene mesh was used in 42 other ...

BACKGROUND AND OBJECTIVES We report our results of a selective approach to primary direct appositional vaginal repair versus transverse rectus abdominis flap repair (TRAM) in patients with extensive rectal/anal cancer or in cases with primary cancer of cervix, vagina or vulva involving the anal canal and anal sphincters. METHODS Eighteen female patients (mean age: 62.9 years; range: 44-81 yea...

Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes. Standard therapy for patients, after surgery and radiotherapy, consists of temozolomide (TMZ), a methylating agent that blocks tumor cell proliferation. Currently, there are no therapies aimed at reducing tumor cell invasion. Ion channels are candidate molecula...