نتایج جستجو برای: transferrin saturation

تعداد نتایج: 57021  

Journal: :Blood 1977
W J Thomas H M Koenig A L Lightsey R Green

Free erythrocyte porphyrin:hemoglobin (FEP:Hb) ratios were determined on 20 infants with iron-deficiency anemia. FEB:Hb ratios were compared with simultaneously drawn serum ferritin and serum transferrin saturation levels. FEP:Hb ratios dropped steadily during treatment of the anemic infants, but remained elevated compared to age-matched nonanemic infants, until the anemia was corrected. FEP:Hb...

A.R Heidarnia M Alizadeh SH Dabiri Z Farahmandi nia Z Jalili

Iron deficiency anemia(IDA) is one of the most common nutritional problems in the world.children under 5 years old are considerd as the high risk group consisting a high proportion of IDA patients.in this group,due to the specific conditions,the complication of anemia may lead to serious consequences.this study was designed to determine the prevalence of IDA in 1-5 years old children.A total of...

Ahmad Tamaddoni, Donya Kheirkhah, Haleh Esmaili, Reza Ghadimi,

Background: The prevalence of obesity is increasing and many countries are struggling with its high rate and serious complications. As a result of distinct diet in obese children, they may be susceptible to nutritional deficiencies in particular, iron deficiency. This study aimed to examine the relationship between obesity and iron indices. Methods: In this cross-sectional study, 206 element...

Journal: :Blood 2006
Rajko Kusec Ozren Jaksic Slobodanka Ostojic Ika Kardum-Skelin Radovan Vrhovac Branimir Jaksic

dependent on iron delivery to developing erythrocytes; increased transferrin saturation may be essential to deliver iron when DMT1 activity is diminished. Thus, even if medications that increase hepcidin levels become available for treatment of iron overload, they may not benefit DMT1 patients because increased plasma hepcidin level would limit release of iron into the bloodstream, decreasing s...

1999
Angel F. Remacha Marina Carrasco M. Pilar Sardá M. Jesús Barceló Montserrat Baiget

Indeed, when the iron content of liver biopsies from HCV-infected patients was measured, there was only a real increase in hepatic iron in 10% of the cases, despite a rise in serum ferritin and transferrin saturation.8 It should be pointed out that cytolysis could have led to the increase in both serum ferritin and transferrin saturation. In conclusion, it is unlikely that the C282Y mutation of...

2017
Chie Ogawa Ken Tsuchiya Naohisa Tomosugi Fumiyoshi Kanda Kunimi Maeda Teiryo Maeda

BACKGROUND Optimal iron levels in patients on hemodialysis are currently unknown, and a higher level than that for the healthy population is usually set for such patients considering the use of erythropoiesis-stimulating agents or the occurrence of chronic inflammation. However, excessive iron causes oxidative stress and impairment of its utilization by cells. Therefore we investigated the rela...

2011
Mohammed Sanad Mohammed Osman Amal Gharib

BACKGROUND Recently, hepcidin expression in adipose tissue has been described and shown to be increased in patients with severe obesity. We tried to assess the effect of obesity on hepcidin serum levels and treatment outcome of iron deficiency anemia in children. METHODS This was a case control study included 70 children with iron deficiency anemia "IDA" (35 obese and 35 non-obese) and 30 hea...

2011
Glenn S Gerhard Ravi Chokshi Christopher D Still Peter Benotti G Craig Wood Mollie Freedman-Weiss Cody Rider Anthony T Petrick

BACKGROUND Gastric bypass surgery is a highly effective therapy for long-term weight loss in severely obese patients, but carries significant perioperative risks including infection, wound dehiscence, and leaks from staple breakdown. Iron status can affect immune function and wound healing, thus may influence peri-operative complications. Common mutations in the HFE gene, the gene responsible f...

Journal: :Human molecular genetics 2011
Konrad Oexle Janina S Ried Andrew A Hicks Toshiko Tanaka Caroline Hayward Mathias Bruegel Martin Gögele Peter Lichtner Bertram Müller-Myhsok Angela Döring Thomas Illig Christine Schwienbacher Cosetta Minelli Irene Pichler G Martin Fiedler Joachim Thiery Igor Rudan Alan F Wright Harry Campbell Luigi Ferrucci Stefania Bandinelli Peter P Pramstaller H-Erich Wichmann Christian Gieger Juliane Winkelmann Thomas Meitinger

The level of body iron storage and the erythropoietic need for iron are indicated by the serum levels of ferritin and soluble transferrin receptor (sTfR), respectively. A meta-analysis of five genome-wide association studies on sTfR and ferritin revealed novel association to the PCSK7 and TMPRSS6 loci for sTfR and the HFE locus for both parameters. The PCSK7 association was the most significant...

Journal: :Turkish journal of haematology : official journal of Turkish Society of Haematology 2007
Miryam Elferchichi Hafedh Abdelmelek Mohsen Sakly

The present work was undertaken in order to investigate the effects of static magnetic field (SMF) on hematopoiesis and iron metabolism in male rats. At thermoneutrality (25°C), the exposition of rats to SMF (128 mT, 1h/day for 5 consecutive days) induced an increase of hematocrit (+12%, p<0.05), hemoglobin (+6%, p<0.05) and mean corpuscular hemoglobin concentration (+9%, p<0.05). SMF exposure ...

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