نتایج جستجو برای: transformed b

تعداد نتایج: 949486  

Journal: :Cancer research and treatment : official journal of Korean Cancer Association 2004
Ki-Young Moon

PURPOSE 7-Bromomethylbenz[a]anthracene is a well-known mutagen and carcinogen. The aim of this study is to determine the mutagenic potency of its two major DNA adducts [N(2)-(benz[a]anthracen-7-ylmethyl)-2'-deoxyguanosine (b[a]a(2)G) and N(6)-(benz[a]anthracen-7-ylmethyl)-2'-deoxyadenosine (b[a]a(6)A)] and the simpler benzylated analogs [N(2)-benzyl-2'-deoxyguanosine (bn(2)G) and N(6)-benzyl-2'...

2011
Ga Bin Park Yeong Seok Kim Hyunkeun Song Seonghan Kim Dong Man Park Wang Jae Lee Dae Young Hur

BACKGROUND Epstein Barr virus (EBV) infected B cells are transformed into lymphoblastoid cell lines. Some researchers suggested some a few similarities between this process and carcinogenesis. We observed the expression of CD80 and CD86, co-stimulatory molecules on EBV-transformed B cells and changes of CD54 expression after stimulation of CD80 and CD86. METHODS CD80 and CD86 were stimulated ...

Journal: :Experimental oncology 2011
M Yurchenko L M Shlapatska O L Romanets D Ganshevskiy E Kashuba A Zamoshnikova Yu V Ushenin B A Snopok S P Sidorenko

AIM To study upstream and downstream events in CD150-mediated Akt signaling pathway in normal human B cells, EBV-transformed lymphoblastoid (LCL) and malignant Hodgkin's lymphoma (HL) B cell lines. METHODS To access protein-protein interaction we applied immunoprecipitation, Western blot analysis and surface plasmon resonance (SPR) technique. A novel modification of SPR technique using reduce...

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