We studied GABAergic signaling in astrocytes of olfactory bulb slices using confocal Ca(2+) imaging and two-photon Na(+) imaging. GABA evoked Ca(2+) transients in astrocytes that persisted in the presence of GABA(A) and GABA(B) receptor antagonists, but were suppressed by inhibition of GABA uptake by SNAP 5114. Withdrawal of external Ca(2+) blocked GABA-induced Ca(2+) transients, and depletion ...

Induction generators (IGs) are becoming important day by day in wind energy conversion. As such the numbers of IGs in a power system are increasing hence posing power quality problems. When large numbers of IGs are switched on or switched off from a circuit give rise to transients in the power system. In this paper authors tried to explore the effect of machine parameters on starting transients...

We propose a exible analysis/synthesis model for transient signals that eeectively extends the Spectral Modeling Synthesis (SMS) parameterization of signals from sinusoids+noise to sinu-soids+transients+noise. The explicit handling of transients provides a more realistic and robust signal model. The model presented is a parametric model for transients that allows for a wide range of signal tran...

Corresponding author: Tel: +49 228 732337 Fax: +49 228 732408 E-mail: [email protected] BACKGROUND: Serum neopterin concentrations rise during activation of the cellular immune system. It is suggested that neopterin interacts with cellular redox mechanisms. This induces oxidative stress, which inhibits intracellular Ca transients in various cell types. In type II alveolar epithelial cells, Ca ...

A common comorbidity of diabetes is skeletal muscle dysfunction, which leads to compromised physical function. Previous studies of diabetes in skeletal muscle have shown alterations in excitation-contraction coupling (ECC)-the sequential link between action potentials (AP), intracellular Ca2+ release, and the contractile machinery. Yet, little is known about the impact of acute elevated glucose...

Cardiac neural crest ablation results in depressed myocardial calcium transients and elevated proliferation in myocardium at a stage when cardiac neural crest cells are not in contact with the myocardium. To test the hypothesis that cardiac neural crest-derived cells, which migrate into the caudal, ventral pharynx at stage 14, block a signal from the ventral pharynx, we cultured stage 12 chick ...

Confocal laser scanning microscopy and fluo 4 were used to visualize local and whole cell Ca(2+) transients within individual smooth muscle cells (SMC) of intact, pressurized rat mesenteric small arteries during activation of alpha1-adrenoceptors. A method was developed to record the Ca(2+) transients within individual SMC during the changes in arterial diameter. Three distinct types of "Ca(2+)...

Mauban, Joseph R. H., Christine Lamont, C. William Balke, and W. Gil Wier. Adrenergic stimulation of rat resistance arteries affects Ca21 sparks, Ca21 waves, and Ca21 oscillations. Am J Physiol Heart Circ Physiol 280: H2399–H2405, 2001.—Confocal laser scanning microscopy and fluo 4 were used to visualize local and whole cell Ca21 transients within individual smooth muscle cells (SMC) of intact,...

We present the results of Monte Carlo simulations of the charge carrier transport in a disordered molecular system containing spatial and energetic disorders using the dipolar glass model. Model parameters of the material were chosen to fit a typical polar organic photoconductor polycarbonate doped with 30% of aromatic hydrazone, whose transport properties are well documented in literature. Sim...