conclusion mature biofilms were found to be much more resistant to antifungal agents and the host immune system than free cells. the factors responsible for high resistance included the complex architecture of biofilms, ecm, increased expression of drug efflux pumps, and metabolic plasticity. objectives the present work investigated certain aspects of the resistance of c. albicans biofilms to d...

 liquefied natural gas (LNG) is the most economical way of transporting natural gas (NG) over long distances. Liquefaction of NG by using vapor compression refrigeration system requires high operating and capital cost. Due to lack of systematic design methods for multistage refrigeration cycles, the conventional approaches of determining optimal cycle configuration are mostly based on trial-an...

Supply chain network design (SCND) problem has recently been gaining attention because an integrated management of the supply chain (SC) can reduce the unexpected/undesirable events and can affect definitely the efficiency of all the chain. A critical component of the planning activities of a manufacturing firm is the efficient design of its SC. Hence, SCND affords a sensitive platform for effi...