BACKGROUND Statins are an important part of the treatment plan for patients with type 2 diabetes. However, patients who are prescribed statins often take less than the prescribed amount or stop taking the drug altogether. This suboptimal adherence may decrease the benefit of statin initiation. OBJECTIVE To estimate the influence of adherence on the optimal timing of statin initiation for pati...

This article examines the organisational structure and strategic plans of the African Telecommunications Union (ATU). Although the ATU has been restructured to include private telecommunications entities as associate members, it remains essentially an inter-governmental agency. The article assesses the benefits of a regional approach to telecommunications reform and proposes that regional econo...

BACKGROUND The needs of the growing population of complex patients with multiple chronic conditions calls for a different approach to care. Clinical teams need to acknowledge, respect, and support the work that patients do and the capacity they mobilize to enact this work, and to adapt and self-manage. Tools that enable this approach to care are needed. METHODS Using user-centered design prin...

We consider the application of planning in network security. In this application, plans represent possible attacks on the network, and network administrators need tools that would allow them to explore the plan space quickly and efficiently. Multiple aspects of this problem require generating and inspecting more than one plan, primarily due to limited information about the possible actions of t...

Objectives In borderline class III malocclusions, the patients can be successfully treated by the orthodontic or surgical modalities, however; there is no consensus about the method with the best results regarding functional and esthetic parameters. The present study aimed to assess the treatment plans provided by academic and non-academic surgeons regarding borderline class III patients. Meth...

Introduction: Chemoradiation is a well-established protocol for management of localized esophageal cancer. However, some early and late toxicities are associated with this therapy. Plan evaluation in term of normal tissue complication probability (NTCP) may help clinicians to tailor this therapy more individually. Given the variety of present radiobiological models, the choice...

Healthcare service providers, including those involved in renal disease management, are concerned about the planning of their patients’ treatments. With efforts to automate the planning process, shortcomings are apparent due to the following reasons: (1) current plan representations or ontologies are too fine grained, and (2) current planning systems are often static. To address these issues, w...