ketotifen is a benzocycloheptathiophene with a range of pharmacological activities. the present study was carried out to evaluate the action of ketotifen on isolated rat bladder contractions induced by kci and acetylcholine, compared with the effects of other drugs. ketotifen (5 µm) reduced the response to acetylcholine on rat isolated bladder without altering the maximum response and shifted t...

repeated bone marrow examination was found to be of value in assessing response to treatment in megaloblastic anemia. the objective of this study was monitoring the response of megaloblastics to treatment, concerning the location of neutrophilic myeloperoxidase and myeloperoxidase index (mpxi) and their variation in megaloblastic erythroid progeny. it is possible to follow up megaloblastic case...

objective: leishmaniasis is one of the six most common parasitic infections in tropical regions. there are different therapeutic modalities. however therapeutic resistance is developed and resulted in numerous problems. so evaluation of other therapeutic modalities is performed extensively. we compared the therapeutic response of cutaneous leishmaniasis with glucantime and garlic extract and it...

Traditional anticancer therapy involves treatment with radiation and DNA-damaging chemotherapies. More recently, insight into the molecular and genetic changes associated with cancer has led to a shift in anticancer drug development, and new drugs typically modulate specific molecular targets associated with onset and progression of the disease. The oncologist’s armamentarium has thus expanded ...

Christine Grella: Jackson’s article challenges us to rethink our entire understanding of drug treatment, expand our definition of who is in treatment, and revise our list of desired outcomes. If the family, not the individual with the drug problem, is the unit of treatment, then what counts as success must include whatever contributes to family members’ well-being and the way the entire family ...

This paper analyzes the identifying power of weak convexity assumptions in treatment effect models with endogenous selection. The counterfactual distributions are constrained either in terms of the response function, or conditional on the realized treatment, and sharp bounds on the potential outcome distributions are derived. The methods are applied to bound the effect of education on smoking. ...

objectives: the rate of person to person transmission of intestinal parasites is high in elderly and mentally retarded patients and lack of treatment may cause disease spread.this sudy was conducted to evaluate the efficacy of treatment of intestinal parasitic infections in elderly and mentallyretardedpatients of golabchi center of kashan. methods & materials: this descriptive study was carried...