Porokeratotic Eccrine Ostial and Dermal Duct Nevus (PEODDN) is a rare disorder of keratinization characterized by the presence of cornoid lamellae and association with eccrine sweat ducts. These lesions are usually benign and asymptomatic, so treatment is often for cosmetic purposes. Current therapies for PEODDN are either insufficient or impractical. We present a case of PEODDN treated with to...

137 The goal of any surgical or aesthetic procedure is to leave no scarring. For this, it is essential that wound healing should be optimised so that the skin heals without scars and as quickly as possible. A lot of research has been done on wound healing, but how much of this translates into actual clinical results remains to be seen. Two reviews in this issue focus on these aspects of wound h...

Background: Acanthosis nigricans (AN) is a brown to black, velvety hyperpigmentation of the skin that usually involves cutaneous folds. Treatment of AN is important regarding cosmetic reasons and various therapeutic modalities have been used for these purposes. The goal of this study was to compare the effectiveness of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate for tre...

BACKGROUND Acne vulgaris is a chronic disease with several pathogenic factors. Multiple medications are typically used that can lead to nonadherence and treatment failure. Combination medications target multiple pathways of acne formation and may offer therapeutic benefit. PURPOSE To explore the efficacy and tolerability of combination retinoid plus antimicrobial treatments in acne vulgaris. ...

Background The improvement of in vitro maturation (IVM) protocols through the supplementation with different molecules has become an alternative to increase the culture medium efficiency. Tretinoin (TTN, all-trans retinoic acid, ATRA), is an active metabolite of vitamin A [1], that mediates cell proliferation, cell differentiation, and embryonic development process. In in vitro production embry...

According to the author, the single most effective component in a skincare regimen for reversal of photoaging is the use of retinoids. Here is a guide to the mechanism and application of various formulations of retinoids, and a comprehensive skin regimen incorporating tretinoin.

preparation of tretinoin-containing microspheres with the aim of reducing undesirable skin reactions towards trans retinoic acid (tra) and thus, improving patient compliance is of particular interest. these microspheres have to be smaller than 30 m m to avoid causing gritty feel when applying on the skin, and slow the release of drug to minimize its skin side effects. following preliminary eval...