We report here that polyethylene glycol (PEG) linked to near infrared dyes conjugated to chimeric mouse-human anti-carcinoembryonic antigen (CEA) antibody greatly improves imaging of liver metastases in a nude mouse model of colon-cancer experimental metastases. PEGylated and non-PEGylated DyLight 650 and 750 dyes were conjugated to the chimeric anti-CEA antibody. The dyes were initially inject...

Covalent derivatization of proteins with fluorescent dyes prior to separation is increasingly used in proteomic research. This paper examines the properties of several commercially available iodoacetamide and maleimide dyes and discusses the conditions and caveats for their use in labeling of proteomic samples. The iodoacetamide dyes BODIPY TMR cadaverine IA and BODIPY Fl C(1)-IA were highly sp...

the used activated carbon was derived from pine-cone and was used for the removal of acid black 1(ab1) and acid blue 113(ab113) dyes. a batch sorption study was carried out in order to obtain optimum isotherm model. the study showed the best fit of the adsorption isotherm data was obtained using the langmuir model for both dyes. the monolayer maximum saturation capacities of ab1 and ab113 dyes ...

Natural dyes are widely used in the coloring of food, leather and wood [1]. Traditionally they were the only colorants for textile fibers like wool, silk, cotton and flax. Their use in textiles declined drastically with the introduction of synthetic dyes in 1856 [2-6]. Presently the use of synthetic dyes is estimated at around 10,000,000 tons per annum [7-11]. The manufacture and use of this la...

Azo dyes are one of the oldest industrially synthesized organic compounds characterized by presence of Azo bond (-N=N-) and are widely utilized as coloring agents in textile, leather, cosmetic, paint, plastic, paper, and food industries During textile processing, inefficiencies in dyeing result in large amounts of the dyestuff (varying from 2% loss when using basic dyes to a 50% loss when certa...

A simple and easy solubility enhancement of basic dyes was performed with bulky and symmetric weakly coordinating anions (WCAs). The WCAs decreased the ionic character of the dyes by broadening the partial charge distribution and causing a screening effect on the ionic bonding. This new modification with WCAs has advantages in that it has no influence on the optical properties of the dyes. The ...

Dyes derived from natural materials such as plant leaves, roots, bark, insect secretions, and minerals were the only dyes available to mankind for the coloring of textiles until the discovery of the first synthetic dye in 1856. Rapid research strides in synthetic chemistry supported by the industrialization of textile production not only led to the development of synthetic alternatives to popul...

Dyes are synthetic organic compounds widely used in various industries such as, textile, leather, plastic, food, pharmaceutical, and paints manufacturing industries. Coloured effluents are highly toxic to the aquatic life and mutagenic to humans. Wastewater containing dyes has become an important issue demanding serious attention. Among the synthetic dyes, azo dyes are the largest and most wide...

Heptamethine cyanine dyes are attractive compounds for imaging purposes in biomedical applications because of their chemical and photophysical properties exhibited in the nearinfrared region. A series of meso amino-substituted heptamethine cyanine dyes with indolenine, benz[e]indolenine and benz[c,d]indolenine heterocyclic moieties were synthesized and their spectral properties including fluore...