Resistance to eprinomectin was suspected in a dairy sheep farm southwestern France. The efficacy of topical and injection formulations against gastrointestinal nematodes (GINs) compared using faecal egg count reduction test. GIN species were identified by real-time PCR, concentrations measured serum High-Performance Liquid Chromatography 2 5 days after treatment. Efficacies 99.6% 86.1% for form...

Dioxapyrrolomycin, pyrrolomycin C, pyrrolomycin D, and piericidin C2 produced by UC 11065 were evaluated as anthelmintics. Assays used to examine these compounds included effects on the free-living nematode Caenorhabditis elegans, ability to clear target nematodes (Haemonchus contortus and Trichostrongylus colubriformis) from jirds, and clearance of Haemonchus contortus from lambs. A crude extr...

The effects of tannins on adult populations of Haemonchus contortus, Trichostrongylus colubriformis and Teladorsagia circumcincta in goats are characterised mainly by a decrease in egg excretion without any significant changes in worm number. In contrast, the impact of tannins on T. colubriformis or T. circumcincta third-stage larvae (L3) is associated with a significant reduction in worm estab...

The helminth burdens of 17 springbok from 2 localities in the Transvaal and of 4 springbok from the western Cape Province were determined. Eight of the animals from the Transvaal and the 4 from the Cape Province were also examined for arthropod parasites. In all, 26 helminth species, 5 species of ixodid ticks and 4 species of lice were recovered from the springbok. Of the helminths Dictyocaulus...

Haemonchus contortus and Trichostrongylus colubriformis are among the most important parasitic nematodes of small ruminants. Caenorhabditis elegans, a free-living nematode, is used as a model for evaluating anthelmintic activity of a variety of test substances. Extracts of several medicinal plants are useful in vitro and in vivo against nematode development. Extracts of Curtisia dentata, a Sout...

Trichostrongylus colubriformis (Strongylida), a small intestinal nematode of small ruminants, is a major cause of production and economic losses in many countries. The aims of the present study were to define the transcriptome of the adult stage of T. colubriformis, using 454 sequencing technology and bioinformatic analyses, and to predict the main pathways that key groups of molecules are link...