Brucellosis is a group of closely associated zoonotic bacterial illnesses caused by members of the genus Brucella. B. melitensis Omp31 is a promising candidate for a subunit vaccine against brucellosis. This study surveyed the immunogenicity of Omp31 alone and with incomplete Freund's adjuvant (Omp31-IFA) and N-trimethyl chitosan (TMC/Omp31) nanoparticles (NPs), as well as the effect of Omp31 i...

Tautomycetin (TMC) is a polyketide metabolite produced by Streptomyces sp. CK4412 and Streptomyces griseochromogenes. This intriguing molecule was previously shown to possess activated T-cell-specific immunosuppressive activity with a novel mode of pharmacological action, both in vivo and in vitro. More recent studies have also revealed promising anticancer activity in a variety of models. The ...

INTRODUCTION The transcription factor nuclear factor-kappa B (NF-κB) is highly involved in regulation of a number of cellular processes, including production of inflammatory mediators. Thus, this transcription factor plays a role in pathology of many diseases, including rheumatoid arthritis, an autoimmune disease hallmarked by an imbalance of pro and anti-inflammatory cytokines. Small nucleic a...

This study explores the congestion dependence relationship among links using microsimulation, based on data from a real road network. The work is motivated by recent innovations to improve the reliability of Dynamic Route Guidance (DRG) systems. The reliability of DRG systems can be significantly enhanced by adding a function to predict the congestion in the road network. This paper also talks ...

The effect of recently derived rat transplantable mammary carcinomas (TMC), the Walker carcinoma 256 (W256) and the Walker carcinosarcoma R256 (WR256) upon the lipid composition of the host liver and muscle was determined. Sephadex column chromatography was employed to separate the nonlipid water-soluble substances and gangliosides from the total pure lipid of chloroform-methanol extracts of ti...

BACKGROUND New smartphone communication technology provides a novel way to provide personalized continuing care support following alcohol treatment. One such system is the Addiction version of the Comprehensive Health Enhancement Support System (A-CHESS), which provides a range of automated functions that support patients. A-CHESS improved drinking outcomes over standard continuing care when pr...

The effect of recently derived rat transplantable mammary carcinomas (TMC), the Walker carcinoma 256 (W256) and the Walker carcinosarcoma R256 (WR256) upon the lipid composition of the host liver and muscle was determined. Sephadex column chromatography was employed to separate the nonlipid water-soluble substances and gangliosides from the total pure lipid of chloroform-methanol extracts of ti...

This study was conducted to determine the effects of feeding a trace minerals-fortified microbial culture (TMC) on the performance and carcass characteristics of late-fattening Hanwoo steers. A mixture of microbes (0.6% [v/w] of Enterobacter sp., Bacillus sp., Lactobacillus sp., and Saccharomyces sp.) was cultured with 99% feedstuff for ensiling and 0.4% trace minerals (zinc, selenium, copper, ...

Transition metal carbides (TMC) are characterized with high melting points which make experimental determination of their average surface energies a difficult task. A database of 3d, 4d and 5d TMC is hereby established using machine learning technique on the platform of support vector regression (SVR). SVR was built, trained and validated using some selected metals in periodic table and accurac...

Metal-superoxo species are involved in a variety of enzymatic oxidation reactions, and multi-electron oxidation of substrates is frequently observed in those enzymatic reactions. A CrIII -superoxo complex, [CrIII (O2 )(TMC)(Cl)]+ (1; TMC=1,4,8,11-tetramethyl-1,4,8,11-tetraazacyclotetradecane), is described that acts as a novel three-electron oxidant in the oxidation of dihydronicotinamide adeni...