this deformity is often reffered to as thumbclutched hand, but a better term is the congenital clasped thumb. the congenital clasped thumb is associated with several well-de-fined syndromes, although it may also present as an isolated abnormality. weckesser, reac, and heiple called it a syndrome and divided the syndrome in to four groups. in group i, the thumb is deficient in extention only. in...

The recent development of advanced high-resolution transducers has enabled the fast, easy, and dynamic ultrasonographic evaluation of small, superficial structures such as the finger. In order to best exploit these advances, it is important to understand the normal anatomy and the basic pathologies of the finger, as exemplified by the following conditions involving the dorsal, volar, and latera...

dislocation of the thumb carpometacarpal joint is a rare injury, and only 38 cases have been definitively described in the english-speaking literature. all the reported dislocations have been dorsal. we present a volar form of the thumb carpometacarpal dislocation which was managed surgically after three months from the injury with open reduction and volar ligament reconstrction, with satisfact...

Cleft hand is an anomaly in which the primary feature is oligodactyly, and it is considered an important congenital malformation. The authors have analyzed the cases they have handled and developed an independent classification based on the number of defective digits. It has been ascertained that the clinical symptoms correlate with the number of defective digits, and a regular pattern was obse...

Topotecan (TPT) is a topoisomerase I (topo I) poison that has shown promising antineoplastic activity in solid tumors and acute leukemia. In the present study, a band depletion assay was used to evaluate the ability of TPT to stabilize topo I-DNA adducts in human leukemia cell lines and in clinical leukemia samples ex vivo. This assay showed that 50% of the cellular topo I in HL-60 human myelom...

This study evaluated the generalization, maintenance, and negative side-effects of Habit Reversal (HR) and Differential Reinforcement of Other Behaviour (DRO) in the elimination of thumb-sucking. Thirty children who sucked their thumbs or fingers excessively were randomly assigned to a HR, DRO or wait-list control group. Observation data were collected in three observation settings. Both proced...

abstract a solitary plasmacytoma of bone occurs in approximately 2-5% of patients with myeloma. the lesion mostly found in the axial skeleton and have infrequently been reported to arise in the hand, and usually occur in the distal phalanges. we report the interesting case of a 75-year-old man who developed a solitary lytic lesion of the thumb proximal phalanx. this lesion was explored through ...