نتایج جستجو برای: triple negative

تعداد نتایج: 572352  

Background & Objective: Our knowledge about correlation of androgen receptor expression and clinicopathological properties of triple-negative breast cancer (TNBC) patients is inadequate, particularly in the Iranian population. The main aim of the present study was to assess the AR expression in TNBC Iranian patients and evaluate its correlation with their clinicopathological pa...

2014
Imen Medimegh Ines Omrane Maud Privat Nancy Uhrhummer Hajer Ayari Fadoua Belaiba Farhat Benayed Khaled Benromdhan Sylvie Mader Ives-Jean Bignon Amel Benammar Elgaaied

INTRODUCTION MicroRNAs are small, non coding regulatory molecules containing approximately 21 to 25 nucleotides. They function as controllers of expression at post transcriptional levels of most human protein-coding genes and play an essential role in cell signaling pathways. The objective of the present study is to evaluate the expression profile of the following micro-RNAs: miR-10b, miR-17, m...

2016
Jingdan Qiu Xinying Xue Chao Hu Hu Xu Deqiang Kou Rong Li Ming Li

PURPOSE Triple-negative breast cancer (TNBC) has attracted more attention both clinically and experimentally because of its high-risk biological characteristics and lacking of effective treatment method. The purpose of this retrospective study was to find out the incidence of triple-negative breast cancer (TNBC) in all kinds of breast cancers and to compare and analyze the clinicopathological f...

2011
Lee H. Chen Wen-Hung Kuo Mong-Hsun Tsai Pei-Chun Chen Chuhsing K. Hsiao Eric Y. Chuang Li-Yun Chang Fon-Jou Hsieh Liang-Chuan Lai King-Jen Chang

Discrepancies in the prognosis of triple negative breast cancer exist between Caucasian and Asian populations. Yet, the gene signature of triple negative breast cancer specifically for Asians has not become available. Therefore, the purpose of this study is to construct a prediction model for recurrence of triple negative breast cancer in Taiwanese patients. Whole genome expression profiling of...

2016
Mingming Lv Pengfei Xu Ying Wu Lei Huang Wenqu Li Shanshan Lv Xiaowei Wu Xin Zeng Rong Shen Xuemei Jia Yongmei Yin Yun Gu Hongyan Yuan Hui Xie Ziyi Fu

Triple negative breast cancer (TNBC) is an aggressive type of breast cancer with high heterogeneity. To date, there is no efficient therapy for TNBC patients and the prognosis is poor. It is urgent to find new biomarkers for the diagnosis of TNBC or efficient therapy targets. As an area of focus in the post-genome period, long non-coding RNAs (lncRNAs) have been found to play critical roles in ...

2009
Sung Hun Kim Jae Jeong Choi Eun Suk Cha Bong Joo Kang Ji Hye Lee So-Yeon Lee Seung Hee Jeong Hyeon Woo Yim Byung Joo Song

JKSMRM 14:95-102(2010) Department of Radiology, College of Medicine, The Catholic University of Korea Clinical Research Coordinating Center, College of Medicine, The Catholic Medical Center Department of Surgery, College of Medicine, The Catholic University of Korea Received; September 27, 2010, revised; November 17, 2010, accepted; December 1, 2010 Corresponding author : Sung Hun Kim, M.D., De...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Rebecca Dent Maureen Trudeau Kathleen I Pritchard Wedad M Hanna Harriet K Kahn Carol A Sawka Lavina A Lickley Ellen Rawlinson Ping Sun Steven A Narod

PURPOSE To compare the clinical features, natural history, and outcomes for women with "triple-negative" breast cancer with women with other types of breast cancer. EXPERIMENTAL DESIGN We studied a cohort of 1,601 patients with breast cancer, diagnosed between January 1987 and December 1997 at Women's College Hospital in Toronto. Triple-negative breast cancers were defined as those that were ...

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