Reduction of phosphine oxides into the corresponding phosphines using PhSiH3 as a reducing agent and Ph3C+[B(C6F5)4]? an initiator is described. The process highly efficient, broad range secondary tertiary alkyl arylphosphines, bearing various functional groups in generally good yields. reaction believed to proceed through generation silyl cation, which with oxide provides phosphonium salt, fur...

A new coupling-isomerization-Claisen domino reaction starting from electron deficient halides and 1-(hetero)aryl propargyl trityl ethers dichotomizes in the concluding steps of the sequence and gives rise to the formation of tricyclo[3.2.1.0(2,7)]oct-3-enes, enones, 1H-isochromenes, or indans as a consequence of minute differences of substituent effects.

Reduction of ribono-1,4-lactones and gulono-1,4-lactone as well as ribono-1,5-lactone and glucono-1,5-lactones with LTBH (1.2 equiv.) in CH2Cl2 at 0 °C for 30 min provided the corresponding pentose or hexose hemiacetals in high yields. Commonly used in carbohydrate chemistry protecting groups such as trityl, benzyl, silyl, acetals and to some extent acyls are compatible with this reduction.

An efficient synthesis of the angiotensin-II inhibitor valsartan (Diovan®) is presented. Directed ortho-metalation of 5-phenyl-1-trityl-1H-tetrazole (6) and its Negishi coupling with aryl bromide 5 are the key steps of the synthesis. This method overcomes many of the drawbacks associated with previously reported syntheses.

Stable configurations and Lamport clocks have garnered improbable interest from both cyberneticists and researchers in the last several years. In our research, we disconfirm the synthesis of thin clients, which embodies the important principles of networking. We construct new mobile theory (TRITYL), which we use to verify that compilers and operating systems are mostly incompatible.

The 2-desoxy-ribose nucleosides, first isolated by Levene and London’ by the hydrolysis of thymus nucleic acid, are characterized by their extreme ease of hydrolysis by very dilute mineral acids. Thus, guanine-2-desoxy-riboside is completely hydrolyzed by heating with 0.01 N hydrochloric acid during 5 minutes. Since the rate of hydrolysis is of the same order as that of the furanosides, it was ...

Synthesis, photophysical properties and submicron ring formation of functionalized uracil morpholino monomers have been reported. A series of characterization techniques indicated that the rings are formed by the inter-molecular hydrogen bonding of the uracil nucleus having a trityl-protected morpholino moiety. This is the smallest nucleoside unit known to date for submicron size ring formation.

The stoichiometric reaction of trityl cation with two equivalents of Ph2PH affords the phosphine stabilized phosphenium salt [Ph2(H)PPPh2][B(C6F5)4] via hydride abstraction, while catalytic amounts of B(p-HC6F4)3 effects catalytic phosphine dehydrocoupling with the liberation of H2. This reaction is accelerated by the presence of olefin or imine, effecting concurrent hydrogenation.

The encapsulation of trityl-functionalised C60 molecules inside carbon nanotubes drastically affects the intermolecular interactions for this species. Whilst the orientations of molecules in the crystal are often controlled by thermodynamics, the molecular orientations in nanotubes are a result of kinetic control imposed by the mechanism of entry into and encapsulation within the nanotube.