BACKGROUND Tuberculosis is the leading causes of mortality among infectious diseases worldwide. The risk of transmission from patients to health workers is doubles that of the general population. The close contact to the infectious case before diagnosis is the major risk for tuberculosis infection. The aim of the study was to assess knowledge and practice of health professionals towards tubercu...

efficient tuberculosis treatment requires the use of good quality medicines. the present study developed a method of dosage by high performance liquid chromatography (hplc) coupled with the dissolution of a combination of fixed doses of four anti-tuberculous (isoniazid, pyrazinamide, ethambutol hydrochlorate, rifampicine). the elaborated protocol was thereafter used to assess the quality of med...

It is unclear if current programmes in China can achieve the post-2015 global targets for tuberculosis - 50% reduction in incidence and a 75% reduction in mortality by 2025. Chinese policy-makers need to maintain the recent decline in the prevalence of tuberculosis, while revising control policies to cope with an epidemic of drug-resistant tuberculosis and the effects of ongoing health reform. ...

Abstract Objectives to analyze the conceptions of people experiencing treatment and diagnosis pulmonary tuberculosis. Method this is a descriptive exploratory research with qualitative approach, developed in School Health Center Belém (Pará) 30 patients. Data was collected during period from September 2019 January 2020 through semi-structured interview aid script containing six questions, as we...

background: tuberculosis (tb) continues to pose a major global health problem and thus intensive action is needed to control and ultimately eliminate the disease . methods: an active case finding (acf) survey was conducted in the urban slum areas of the r-south municipal ward of mumbai city for a period of two months from june to july 2012. micro planning for survey was done by district tubercu...

background: tuberculosis (tb) is a major cause of death worldwide. finding an effective vaccine against tb is the best way to control it. several vaccines against this disease have been developed but none are completely protective. the aim of this study was to design and construct a cloning vector containing the mycobacterium tuberculosis (m. tuberculosis) heat shock protein x (hspx). methods: ...

BACKGROUND Tuberculosis is an urgent public health problem caused by Mycobacterium tuberculosis infection. Many factors, including host genetic factors, are involved in tuberculosis pathogenesis. The SLC11A1 gene (formerly NRAMP1) is a primary candidate for association with tuberculosis susceptibility. METHODS We examined the association between SLC11A1 polymorphisms and susceptibility to tub...

Rapid scale-up of antiretroviral treatment programmes is happening in Africa, driven by international advocacy and policy directives and supported by unprecedented donor funding and technical assistance. This welcome development offers hope to millions of HIV-infected Africans, among whom tuberculosis is the major cause of serious illness and death. Little in the way of HIV diagnosis or care wa...

tuberculosis is one of the most common infectious diseases in the world. in recent years, genetically approach has been developed. one of the interesting gene for investigator is ifn-γr1. in this study we determind susceptibility to tuberculosis with polymorphism of ifn-γr1 gene. fifthly patients with smear positive tuberculosis have been chosen randomly. they were matched with 54 healthy contr...