نتایج جستجو برای: tumor necrosis factor superfamily

تعداد نتایج: 1221977  

Journal: :Advances in experimental medicine and biology 2011
Hao Wu Yu-Chih Lo Qian Yin

NF-κB proteins are evolutionarily conserved master regulators of immune and inflammatory responses (Gilmore, 2006). They play critical roles in a wide array of biological processes including innate and adaptive immunity, oncogenesis and development. They are activated in response to ligation of many receptors including T-cell receptors, B-cell receptors, members of the tumor necrosis factor (TN...

Journal: :Cancer research 2003
Jennifer Walter-Yohrling Xiaohong Cao Michele Callahan William Weber Sharon Morgenbesser Stephen L Madden Clarence Wang Beverly A Teicher

To systematically identify genes related to invasion a three-dimensional multicellular matrix invasion assay was used to classify human tumor cell lines as stromal invasion positive or stromal invasion negative. Cells from two of the primary cell types of the stromal compartment [endothelial cells (HMVEC) and myofibroblasts (HDF)] were assayed for invasion into tumor cell clusters (breast carci...

Azar Baradaran Farahnaz Mardanian Fatemeh Sadat Mostafavi, Roshanak Abutorabi Yasaman Zarrin

Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...

Journal: :iranian red crescent medical journal 0
hamid reza naderi faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran; faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran. tel: +98-9153145632, fax: +985138591057 fereshte sheybani faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran susan rezaei pajand faculty of medicine, department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran

conclusions special high-risk groups, including patients with ltbi, should be treated before receiving tnf-α inhibitors. the tuberculin skin test (tst) is a somewhat cost-effective test for the diagnosis of ltbi. however, its usefulness with respect to false results should be re-evaluated in this situation. results there were somewhat different approaches proposed by various researchers regardi...

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