A 62 year old woman presented to eye casualty with a 10 day history of a left sided headache. Two days after her headache started she developed a painful and pruritic left sided rash. During the 24 hours before presentation, her left eye had become injected, painful, and photophobic. On examination she had a well demarcated, unilateral area of erythematous andmildly oedematous skin, which exten...

BACKGROUND Kissing nevus is a congenital nevus in adjacent parts of the eyelids. Malignant transformation of kissing or divided nevi of the eyelids is rarely described. OBJECTIVE To report a very rare case of malignant transformation of kissing nevus with ocular and extraocular spread. CASE A 57- year- old man with 6/6 visual acuity in both eyes presented with a kissing nevus present since ...

We propose a novel universal acoustic characterization approach to spoken language identification (LID), in which any spoken language is described with a common set of fundamental units defined “universally.” Specifically, manner and place of articulation form this unit inventory and are used to build a set of universal attribute models with data-driven techniques. Using the vector space modeli...

This paper presents the large-eddy simulation of the lid-driven cubic cavity flow by the spectral element method (SEM) using the dynamic model. Two spectral filtering techniques suitable for these simulations have been implemented. Numerical results for Reynolds number Re = 12000 are showing very good agreement with other experimental and DNS results found in the literature.

Discontinuous velocity boundary data for the lid driven cavity flow has long been causing difficulties in both theoretical analysis and numerical simulations. In finite element methods, the variational form for the driven cavity flow is not valid since the velocity is not in H. Hence standard error estimates do not work. By using only W1,r (1 < r < 2) regularity and constructing a continuous ap...

Whenever inference for variance components is required, the choice between one-sided and two-sided tests is crucial. This choice is usually driven by whether or not negative variance components are permitted. For two-sided tests, classical inferential procedures can be followed, based on likelihood ratios, score statistics, or Wald statistics. For one-sided tests, however, one-sided test statis...

Levodopa remains the mainstay of treatment for Parkinson disease (PD), but its use is associated with dyskinesias (LID) in many patients. LID likely reflect dysregulated release of dopamine combined with altered postsynaptic mechanisms due to pulsatile dopamine receptor stimulation. Dopamine D receptors are increased in animal models of LID, and experimental LID is attenuated by suppression of ...

We propose a new two-level nonlinear additive Schwarz preconditioned inexact Newton algorithm (ASPIN). The two-level nonlinear preconditioner combines a local nonlinear additive Schwarz preconditioner and a global linear coarse preconditioner. Our parallel numerical results based on a lid-driven cavity incompressible flow problem show that the new two-level ASPIN is nearly scalable with respect...