abstract objective: thyroid dysfunction complicates the metabolic derangement observed in diabetes mellitus (dm). it is necessary to recognize and treat it, when present, in order to achieve stability of metabolic control in these patients. the aim of this study was to investigate the effect of dm on thyroid hormone levels and other biochemical variables. materials and methods: to determine the...

Cardiovascular disease is the leading cause of morbidity and mortality for patients with type 2 diabetes mellitus (T2DM), accounting for two thirds of patient deaths. In addition to traditional cardiovascular risk factors, hyperglycemia and multiple other factors associated with T2DM such as obesity, insulin resistance, and inflammation play significant roles in cardiovascular disease risk.1 Pa...

Background There is an epidemic of obesity and Type-2 Diabetes Mellitus (T2DM) in the developed world. Subclinical diastolic dysfunction in diabetes is associated with the development of overt heart failure. Although diabetic cardiomyopathy is well documented in older adults with T2DM there are scarce data on younger adults and no published CMR data. We aimed to assess the prevalence and potent...

conclusions depression and anxiety have higher prevalence among diabetic patients and some sociological factors such as age, gender, job and education are related to these psychological disorders. objectives this study aimed to evaluate the prevalence of depression and anxiety among diabetic patients with regards to some factors such as age, gender, level of education and occupational status. m...

Seasonal variation in blood pressure (BP) has been observed in different populations. However, only few studies have focused on BP seasonality in diabetic patients. This study examined the seasonal patterns in BP in 62,589 patients with type 1 diabetes mellitus (T1DM) and in 99,546 patients with type 2 diabetes mellitus (T2DM) from the German/Austrian Diabetes Follow-up Registry. Adjusted mean ...

Type 2 diabetes mellitus (T2DM) is a global pandemic, as evident from the global cartographic picture of diabetes by the International Diabetes Federation (http://www.diabetesatlas.org/). Diabetes mellitus is a chronic, progressive, incompletely understood metabolic condition chiefly characterized by hyperglycemia. Impaired insulin secretion, resistance to tissue actions of insulin, or a combin...

Objective: Type 2 diabetes mellitus (T2DM) is a multifactorial disorder with various disturbances in biochemical processes such as antioxidant status and lipid peroxidation. The aim of present study was evaluation of the oxidative stress markers in saliva of T2DM patients. Materials and Methods: In this study, 80 (40 T2DM and 40 control) individuals were assessed. The salivary total antioxidan...

BACKGROUND Recent studies have demonstrated that immune factors might have a role in the pathophysiology of insulin resistance and type 2 diabetes mellitus (T2DM). Inappropriate glycemic control in patients with T2DM is an important risk factor for the occurrence of diabetes complications. The prevalence of celiac disease (CD) is high in type 1 diabetes mellitus however, there are scarce data a...

Insulin degludec/insulin aspart (IDegAsp) is the first soluble co-formulation which combines two insulin analogues, and provides effective basal and prandial glycemic coverage. It has been assessed as basal insulin in type 2 diabetes mellitus (T2DM), and as part of basal-bolus regime in both type 1 diabetes mellitus and T2DM. Insulin degludec has also been assessed as flexibly administered basa...

Subclinical left ventricular (LV) dysfunction is highly prevalent in people with type 2 diabetes mellitus (T2DM) and independently associated poor cardiovascular outcome ([1][1]). Sodium-glucose cotransporter inhibitors (SGLT2i) have been shown to reduce hospitalizations for heart failure