OBJECTIVE To determine the association of leptin with insulin resistance, body composition, and lipid parameters in postmenopausal women and men with type 2 diabetes mellitus (T2DM). METHODS This study was conducted in 158 patients (87 postmenopausal women and 71 men) with T2DM, and 99 healthy controls (52 postmenopausal women and 47 men). Type 2 diabetes mellitus patients were selected conse...

BACKGROUND Human immunodeficiency virus (HIV) infection and the use of antiretroviral therapy (ART) may increase the risk of type 2 diabetes mellitus (T2DM). However, data from regions with a high burden of HIV/AIDS are limited. We determined the prevalence of T2DM at the time of presentation to a large HIV clinic in Nigeria, as well as the incidence of diabetes 12 months following ART initiati...

Sodium glucose co-transporter 2 (SGLT-2) inhibitors are newly developed but promising medicine for type 2 diabetes. However, patients with a different renal threshold for glucose excretion (RT(G)) may have a different reaction to this medicine. Therefore, the objective of this study was to investigate the characteristics of RT(G) and its impact factors in patients with type 2 diabetes mellitus ...

Background and AimsMost data on liver assessment in type 2 diabetes mellitus (T2DM) patients are from retrospective cohorts with selection bias. We aimed at appraising the feasibility, results, benefits of an outpatient systematic noninvasive screening for metabolic dysfunction-associated fatty disease (MAFLD) severity determinants T2DM patients.

background: considerable evidence suggests that oxidative stress affects diabetes mellitus (dm) and contributes to its complications. vitamin d has been shown to possess antioxidant properties. the aim of this study was to determine the association between serum levels of calcifediol (25-oh-d), an indicator of vitamin d status, and lipid profiles with oxidative stress in patients with type 2 di...

abstract objective: it has been reported that adenosine deaminase (ada) is a good marker for insulin function but its clinical significance in type 2 diabetes mellitus (t2dm) is not yet characterized. this study aims to assess the association of ada with glycated hemoglobin (hba1c) and uric acid (ua) in t2dm patients. materials and methods: the study population consisted of 120 subjects divided...

BACKGROUND Health-related quality of life studies among adults with type 2 diabetes mellitus, using the EQ-5D, have been short term and have not assessed change over years. This study assessed the change in health status and health-related quality of life over 5 years among individuals with and without diabetes. METHODS Respondents to the US Study to Help Improve Early evaluation and manageme...

sodium-glucose co-transporter 2 (sglt2) inhibitors are a new glucose-lowering therapy for t2dm with documented benefits on blood glucose, hypertension, weight reduction and long term cardiovascular benefit. they have an inherent osmotic diuretic effect and lead to some volume loss and possible dehydration. there is some concern about the safety of using sglt2 inhibitors in muslim type 2 diabete...

background: type 2 diabetes mellitus (t2dm) and periodontitis are infl ammatory conditions with a bidirectional association. this pilot study aimed to evaluate whether t2dm and glycemic control interfere in infl ammatory markers profi les in gingival crevicular fl uid (gcf) in periodontitis patients. materials and methods: fourteen diabetic periodontitis patients were enrolled in this study, se...

BACKGROUND Endothelial dysfunction plays a central role in atherosclerotic progression and cardiovascular complications of type 2 diabetes mellitus (T2DM). Given the role of nitric oxide in the vascular system, we aimed to test hypotheses of synergy between the common endothelial nitric oxide synthase (eNOS) Asp298 allele and T2DM in predisposing to acute myocardial infarction (AMI). METHODS ...