The soft X-ray absorption spectroscopy (XAS) spectra of Alanine, L- and D-phenylalanine, D-tyrosine dissolved in a solid state were measured at BL17SU SPring-8. exhibited characteristic features dependent on the molecular structure. It was found that almost same obtained for Alanine Phenylalanine, while Tyrosine, spectral shape indicated drastic change owing to existence oxygen 1s → π* transiti...

introduction: gastrointestinal stromal tumors (gists) are the most common mesenchymal neoplasms of the gastrointestinal tract. gist has been shown to over-express c-kit (cd117), the receptor tyrosine kinase. imatinib (sti571 or glivec) is a new type of tyrosine kinase inhibitor that selectively inhibits various tyrosine kinases and has been successfully used to treat gist. in this study we have...

background: the b-cell defect in x-linked agammaglobulinemia (xla) is caused by mutations in the gene for bruton's tyrosine kinase (btk). btk mutations result in deficient expression of btk protein in peripheral blood monocytes. methods: using the anti-btk monoclonal antibody (48-2h), a flow cytometric analysis of intra cytoplasmic btk protein expression in monocytes was performed to ident...

hydrates are crystalline compounds similar to ice, with guest molecules like methane and ethane trapped inside cavities or cages formed by the hydrogen bounded framework of water molecules. these solid compounds give rise to problems in the natural gas oil industry because they can plug pipelines and process equipments. low dosage hydrate inhibitors are a recently developed hydrate control tech...

Abstract We report our investigation of the utility peptide crosslinking cytochrome P450 enzymes from biarylitide biosynthesis to generate a range cyclic tripeptides simple synthons. The crosslinked produced by this include both tyrosine‐histidine (A− N −B) and tyrosine‐tryptophan O tripeptides, latter rare example phenolic crosslink an indole moiety. Tripeptides are easily isolated following p...