Methods All patients presenting to the MDFT with active ulceration during 2010 had their ulcer classified using the Texas system and were entered into the audit. These ulcers were then monitored until healing or until the end of the data collection period (December 2012). A patient with multiple ulcer sites had each ulcer monitored separately. The average healing rates could then be calculated ...

abstractintroduction: diabetes mellitus is the most common human metabolic disease and chronic non healing diabetic foot ulcers are a critical complication for these patients. angipars is a new herbal extract which has been introduced to accelerate healing of these ulcers. the purpose of this study was to investigate the efficacy and safety of oral angipars in patients with chronic diabetic foo...

Triple therapy was given to 49 chronic helicobacter pylori positive chronic duodenal ulcer cases to see its efficacy in H. pylori clearance, eradication and ulcer healing. H. pylori clearance and eradication rates at week 5 and 8 were 87.8% and 81.5% while ulcer healing rates 68.2% and 81.5% respectively. Seven (18%) cases failed to clear H. pylori and were classified as non-responders. Histolo...

A previous study has demonstrated that locally administered growth factors such as epidermal growth factor, basic fibroblast growth factor and hepatocyte growth factor can accelerate healing of experimental gastric ulcers in rats. That study indicates that locally administered growth factors can exert potent biological effects resulting in enhanced gastric ulcers healing. However, the fate of i...

BACKGROUND The total contact cast is considered to be an effective method of off-loading a diabetic non-infected pressure ulcer. However complications have been reported in 1 to 15% of cases, e.g. prolonged healing of the ulcer. Debridement with modern dressings has been reported to be effective in promoting wound healing; however there have been few reported studies of the combination of moder...

BACKGROUND Peptic ulcer disease is the cause for dyspepsia in about 10% of patients. 95% of duodenal and 70% of gastric ulcers are associated with Helicobacter pylori. Eradication of H pylori reduces the relapse rate of ulcers but the magnitude of this effect is uncertain. OBJECTIVES The primary outcomes were the proportion of peptic ulcers healed initially and proportion of patients free fro...

BACKGROUND Treatment of Helicobacter pylori infection prevents duodenal ulcer relapse. It has not been established if treatment of the infection heals duodenal ulcer. AIM To test the hypothesis that treatment of the infection was associated with healing of duodenal ulcer. METHODS A randomised, double blind placebo controlled trial was performed to study the efficacy of an antibiotic only re...

Zinc has been reported to exert a gastroprotective action against various experimental gastric lesions suggesting that this trace element is involved in the integrity of the gastric mucosa. Compounds containing zinc, such as polaprezinc, were developed in Japan and used as an antiulcer drugs in the treatment of human peptic ulcer disease. However, the precise mechanism of Zn(2+) containing comp...

This quasi-experimental research design study aimed to determine the effects of a community-based discharge-planning model for continuing pressure ulcer care on the nutritional status, wound-healing, and infection rates in one hundred elderly patients at a tertiary hospital in Thailand. The patients were simple randomized into two groups; namely, the control group receiving regular care and the...

The relation between intragastric acidity and duodenal ulcer activity was studied prospectively in 21 patients with endoscopically proved duodenal ulcers. The 24 hour intragastric acidity was measured on four separate occasions by continuous recording using combined glass electrodes: (a) in the presence of an ulcer crater without treatment; (b) during active ulceration being treated with raniti...