Umbilical artery catheters have been associated with thrombotic complications, such as partial or complete occlusion in the aorta, the renal arteries, and other blood vessels. There have been few reports of the long-term consequences of either symptomatic or asymptomatic thrombi. We report a patient, now 22 years of age, born with a normal aorta, who developed hypertension at the age of 2 month...

OBJECTIVE The aim of this study was to examine the possible association between umbilical artery pulsatility index (PI) at 10-14 weeks of gestation and either increased fetal nuchal translucency (NT) or fetal chromosomal abnormality. DESIGN This was a prospective study of women undergoing chorionic villus sampling (CVS). SUBJECTS A total of 458 women undergoing CVS were studied; in 418 case...

OBJECTIVE To compare umbilical and middle cerebral artery Doppler ultrasound values in high and low risk pregnancies withfoetal outcome. DESIGN Descriptive prospective study. SETTING Aga Khan University Hospital, Nairobi between the months of February and November 2007. SUBJECTS One hundread and twenty one consecutive female subjects, between 24 and 443 years of age, at or over 28 weeks g...

AIM To study the role of Doppler imaging in prediction of high-risk pregnancies and their outcomes. METHODS AND MATERIAL This prospective study in a setup of tertiary-level care center includes 500 high-risk pregnant women from rural and urban sectors and evaluates the predictive values of various Doppler indices. RESULTS Out of 500 patients, 110 patients had abnormal Doppler among them, 70...

OBJECTIVE To address the possible risk factors, eventual pregnancy outcomes, and probable troubles in follow-ups of pregnancies complicated by an isolated single umbilical artery and to provide data on Turkish cases in such an aspect that ethnic divergences may have influence. MATERIAL AND METHODS A total of 16568 singleton pregnancies that were delivered between May 2006 and May 2013 were re...

To verify that apoptosis is one of the possible mechanisms of neonatal vascular remodeling during the transition from fetal to neonatal circulation, we assayed for apoptosis and evaluated the expression of apoptosis-regulatory proteins in umbilical vessel versus ascending aorta, ductus arteriosus (DA) versus adjacent pulmonary artery and aorta, or aorta versus its branching arteries. Twenty-two...

OBJECTIVE To assess the diagnostic power of the umbilical venous-arterial index (VAI) for the prediction of poor fetal outcome. SUBJECTS AND METHODS This was a retrospective, cross-sectional clinical study in which normalized umbilical vein blood volume flow rate (nUV) (mL/min/kg estimated body weight), umbilical artery pulsatility index (UAPI), the newly developed VAI (nUV/UAPI), and the ute...

OBJECTIVE To develop national guidelines on the use of fetal Doppler in obstetrics. OPTIONS Whether umbilical cord artery, umbilical cord venous, ductus venosus, and middle cerebral artery Doppler are useful in assessing fetal health. OUTCOME Prediction of adverse perinatal outcome or prediction of fetal anemia. EVIDENCE MEDLINE search and review of bibliographies in identified articles. ...

BACKGROUND The aim of the study was to evaluate the relation between maternal placental Doppler velocimetry, levels of the maternal glucose, and clinical signs of vasculopathy in pregnancy complicated by pregestational diabetes mellitus. METHODS AND RESULTS A retrospective study of 155 pregestational diabetic women between the 22nd and 40th weeks of pregnancy, categorized in White classificat...

The Hyrtl anastomosis is a common connection between the umbilical arteries near the cord insertion in most human placentas. It has been speculated that it equalizes the blood pressure between the territories supplied by the umbilical arteries. However, its functional role in the regulation and distribution of fetal blood flow to the placenta has not yet been explored. A computational model has...