The complexity of the nonsense-mediated decay (NMD) system makes it difficult to study by comparing the expression of various single reporter constructs+ The known effects of the NMD genes include a reduction both in mRNA stability (reviewed by Czaplinski et al+, 1999) and in the efficiency of translational initiation (Muhlrad & Parker, 1999) of nonsense-containing plasmids as well as an appare...

Using group model building we developed a series of causal loop diagrams identifying the environmental impacts ultra-processed food (UPF) systems, and underlying system drivers, which was subsequently validated against peer-reviewed literature. The final conceptual displays commercial, biological social drivers UPF system, on sub-systems including climate, land, water waste. It complex interact...

IGNACIO RIBERA & ARNAUD FAILLE Institute of Evolutionary Biology (CSIC-UPF), Passeig Maritim de la Barceloneta 37-49, E-08003 Barcelona, Spain. E-mail: [email protected] Museo Nacional de Ciencias Naturales, José Gutiérrez Abascal 2, E-28006 Madrid, Spain. Département Systématique et Evolution, Muséum National d’Histoire Naturelle, Bât. Entomologie, 45 rue Buffon, F-75005 Paris, Fr...

Present Address : Max Planck Institute for Molecular Cell Biology and Genetics, Dresden 01277 : EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), Dr. Aiguader 88, 08003 Barcelona, Spain & Universitat Pompeu Fabra (UPF), Barcelona, Spain. : Research Center Borstel, Borstel, 23845, Germany ^: Department of Anesthesia and Perioperative Care, Genentech Hall, 600 16 Street...

The open reading frame at 86.7 min on the Escherichia coli chromosome, "yigC," complemented a ubiD mutant strain, AN66, indicating that yigC is the ubiD gene. The gene product, a 497-amino-acid-residue protein, showed extensive homology to the UPF 00096 family of proteins in the Swiss-Prot database.

ICREA-Complex Systems Lab, Universitat Pompeu Fabra, Dr. Aiguader 80, 08003 Barcelona, Spain Dep. of Physics and Chemistry, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark Santa Fe Institute, 1399 Hyde Park Road, Santa Fe NM 87506 USA Institut de Biologia Evolutiva, CSIC-UPF, Passeig Maritim de la Barceloneta, 37-49, 08003 Barcelona, Spain [email protected], harold@ifk...

Jose Luis Sardina, Bruno Di Stefano, and Thomas Graf Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA; Harvard Stem Cel...

We present a formal model of network protocols and their application to modeling firewall policies. The formalization is based on the Unified Policy Framework (UPF). The formalization was originally developed with for generating test cases for testing the security configuration actual firewall and router (middle-boxes) using HOL-TestGen. Our work focuses on modeling application level protocols ...