BACKGROUND Little is known about muscle mass loss in early stage chronic kidney disease (CKD). We used 24-hour urinary creatinine excretion rate to assess determinants of muscle mass and its evolution with kidney function decline. We also described the range of urinary creatinine concentration in this population. METHODS We included 1072 men and 537 women with non-dialysis CKD stages 1 to 5, ...

Haag and Larson (1) demonstrated in 1942 that in the case of nicotine the extent of urinary excretion of a chemical may be related to the reaction of urine. They emphasized the importance of taking into consideration the dissociation constant of a drug and the relative reabsorbability of the free and dissociated base. Extending these studies to the urinary excretion of quinine in man, Haag, Lar...

Cholesterol and ascorbic acid of adrenals are significantly diminished in scorbutic guinea pigs (1). As these substances appear to be related to the formation of adrenal cortical hormone (a), it has been indicated that the secretion of this hormone might diminish in scurvy. The urinary excretion of 17-ketosteroids in females is said to depend almost entirely on the activity of the adrenal corte...

Familial renal glycosuria (FRG) is an inherited disorder characterized by persistent glycosuria in the absence of hyperglycemia. It is caused by mutations in the sodium-glucose co-transporter, leading to increase in the renal excretion of glucose and sodium. However, there have been no studies on the role of fasting and postprandial changes in the urinary sodium excretion in patients with FRG. ...

Background: The iodine deficiency elimination program that began two decades ago resulted in Iran becoming an iodine deficiency disorders free country in the Middle East region. The present study was performed to evaluate the adequacy of iodine supplementation after 17 years of universal salt iodization in Fars province. Methods: In a cross-sectional study, 1200 schoolchildren (480 girls and 72...

In order to determine the value of dipstick analysis of urinary protein in pregnancy induced hypertension, a prospective study analyzing pregnant patients with a diagnosis of hypertensive disorder was conducted to compare the result of urinary protein dipstick analysis with 24hr. urine protein collection in obstetrical clinics affiliated to Shiraz University of Medical Sciences. All patien...

The urinary excretion rate is calculated based on short-term, defined time sample collections with a known sample mass, and this measurement can be used to remove the variability in urine concentrations due to urine dilution. Adjustment to the urinary excretion rate of hippuric acid was evaluated in 31 healthy volunteers (14 males and 17 females). Urine was collected as short-term or spot sampl...

the whole plant, pergularia daemia (family: asclepediaceae), was extracted with 50% alcohol and a fresh batch of the plant material was successively extracted with petroleum ether, ethyl acetate and n-butanol to determine its diuretic activity. the diuretic activity of the different extracts at a dose of 400 mg/kg was assessed orally in rats with furosemide as a standard drug using lipschitzs t...

This study evaluated urinary fluoride excretion by school children 4-6 years old who were living in a south Texas rural community that had concentrations of fluoride in drinking water supplies generally around the optimal level. We took supervised collections of urine samples in the morning and afternoon at school, and parents of the participating students collected nocturnal samples. We record...