We determined the urinary excretion, expressed as the protein/creatinine ratio (morning urines), of albumin (a marker of glomerular dysfunction) and retinol-binding protein (RBP; a low-molecular-mass protein marker of tubular proteinuria) in 102 non-insulin-dependent diabetic patients. There was a statistically significant (P < 0.0001) correlation (rho = 0.38) between the urinary excretion valu...

In clinical studies of statins (class of drugs lowering plasma cholesterol levels), transient low-molecular-weight proteinuria was observed. The causes of statin-induced proteinuria in the patient background of those studies (cardiovascular and kidney disease) are multifactorial and, therefore, a matter of debate. In light of this, it seemed interesting to investigate the effect of statins on t...

Abstract Background Lupus nephritis can be seen in up to 60% of all SLE patients with 10–15% progressing end-stage renal disease; late diagnosis lupus is correlated a higher frequency insufficiency. The study aim determination the value urinary human epidermal growth factor (urinary EGF) as an early biomarker and its relevance disease activity histopathology. Results included 58 30 healthy cont...

Study Objective: To find the diagnostic and pathogenetic significance of endogenous proteins in infants toddlers with urinary tract infections (UTIs). Design: controlled clinical trial. Materials Methods. We examined 34 children UTIs aged 29 days to 2 years 11 months days. The control group included 20 healthy children. All subjects underwent measurement serum hepatic intestinal fatty acid-bind...

previous work by other investigators indicates a direct relation between the amount of protein in the diet and the level of urea in the blood . however, the present report shows that the type of protein , apart from its level in the ration , also has an effect on blood urea concentrations. when adult male or female rats of two strains were fed a ration in which the only source of protein was wh...

For centuries, physicians have attempted to use the urine for noninvasive assessment of disease. Today, urinalysis, in particular the measurement of proteinuria, underpins the routine assessment of patients with renal disease. More sophisticated methods for assessing specific urinary protein losses have emerged; however, albumin is still the principal urinary protein measured. Changes in the pa...

BACKGROUND We aimed to evaluate urinary MCP-1 and oxidative stress through urinary malondialdehyde (MDA) in leprosy and correlate them with traditional, but less sensitive markers of renal disease. METHODS This is a cross-sectional study of 44 patients with diagnosis of leprosy and no previous treatment. Skin smear was assessed through a bacteriological index - from 0 to 6+. Glomerular filtra...