OBJECTIVE To examine the association between adolescents' perception of clinician communication and adolescents' reported acceptability of the steps involved in chlamydial screening during urgent care visits. DESIGN Cross-sectional survey of adolescents after urgent care visits. SETTING Four pediatric clinics in a health maintenance organization. PARTICIPANTS Three hundred sixty-five adol...

Thirty-seven young healthy subjects with normal renal function were studied to assess the quantitative effect of protein intake on creatinine clearance. A standard 24-h urine collection and blood sample at the end of the collection were obtained for creatinine and urea concentrations. Correlations between creatinine clearance and urinary urea nitrogen excretion (r = 0.8; P less than 0.0001) and...

Huestis and Cone reported in [J. Anal. Toxicol. 22 (1998) 445] that serial monitoring of D-THC-COOH/creatinine ratios in paired urine specimens collected at least 24 h apart could differentiate new drug use from residual D-THC-COOH excretion following acute marijuana use in a controlled setting. The best accuracy (85.4%) for predicting new marijuana use was for a D-THC-COOH/creatinine ratio 0.5...

BACKGROUND Measuring the 24-hour urine protein ≥300 mg is the standard threshold value for diagnosis of preeclampsia. OBJECTIVE This study was intended to determine if a patient's 4-hour urine protein correlate with the 24-hour value for diagnosis of preeclampsia. MATERIALS AND METHODS This was a cross sectional study performed on 84 women with suspected preeclampsia due to positive urinary...

It is difficult to describe hydration status and hydration extremes because fluid intakes and excretion patterns of free-living individuals are poorly documented and regulation of human water balance is complex and dynamic. This investigation provided reference values for euhydration (i.e., body mass, daily fluid intake, serum osmolality; M +/- SD); it also compared urinary indices in initial m...

INTRODUCTION The importance of hydration is undoubtable but reliable data on hydration status and its relation with diet is lacking. OBJECTIVES We aimed to evaluate the hydration status and its relation to beverages and food intake in children. METHODS A sample of 172 (50% male), 7-11 year-old children was included in this survey. Participants completed a 24 h urine collection; a 24 hours f...

BACKGROUND Median urine iodine concentration (UIC; μg/L) in spot urine samples is recommended for monitoring population iodine status. Other common measures are iodine:creatinine ratio (I/Cr; μg/g) and estimated 24-hour urine iodine excretion (UIE; I/Cr × predicted 24-hour Cr; μg/day). Despite different units, these measures are often used interchangeably, and it is unclear how they compare wit...

OBJECTIVES To assess the feasibility and acceptability of home screening for repeat chlamydial infection using urine test kits sent through the mail. METHODS A letter offering home rescreening was mailed to 399 adults who previously tested positive for chlamydia. Kits were then mailed to anyone who did not actively decline. The home testing kits contained instructions on how to collect a urin...

In this article we examine sampling strategies and analytical methods used in a series of recent studies of children's exposure to pesticides that may prove useful in the design and implementation of the National Children's Study. We focus primarily on the experiences of four of the National Institute of Environmental Health Sciences/U.S. Environmental Protection Agency/ Children's Centers and ...

By J. W. ADAMSON, R. ALEXANIAN, C. MARTINEZ AND C. A. FINCH E RYTHROPOIESIS IS BELIEVED to he regulated by a humoral substamice, erythropoietin, which is elaborated in response to tissue need for oxygen. The presence of erythropoietin in the normal individual has been difficult to demonstrate due to limitations in methods currently available for its measurement. The purpose of this study is to ...