Inflammatory joint diseases are characterized by enhanced extracellular matrix degradation which is predominantly mediated by cytokine-stimulated upregulation of matrix metalloproteinase (MMP) expression. Besides tumour necrosis factor-alpha (TNF-alpha), Interleukin-1beta (IL-1beta) produced by articular chondrocytes and synovial macrophages, is the most important cytokine stimulating MMP expre...

Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. Our hypothesis was that whole plant extracts selected according to ethnobotanical sources of historical use might contain multiple molecules with an...

BACKGROUND The common nettle (Urtica dioica L.) is co-associated with willows (Salix spp.) in riparian habitats across Europe. We sampled the widespread nettle psyllid, Trioza urticae (Linné, 1758), from Urtica in willow habitats on a megatransect of Europe from the Aegean to the Arctic Ocean. The aim of this study was to use an unusually widespread insect to assess the influence of geographic ...

This study investigated the vitamin contents and health benefits of nine wild plants consumed as food, medicine, or animal feed in around Elazığ Malatya, Turkey. The introduced Rheum ribes, Gundelia tournefortii, Tragopogon reticulatus, Urtica dioica, Asphodelus aestivus, Medicago sativa, Nasturtium officinale, Mentha pulegium, Capsella pastoris. results showed that were common ingredients Turk...

urtica dioica l. is an iranian native pharmacological plant for which little attention has been paid to the anatomical structure. medical applications of this plant include diabetes therapy, digestive improvement, anemia and kidney disease therapy. because climatic conditions can affect the anatomical structure which in turn affects pharmacological compositions, research on the anatomy of this ...

objective: oxidative stress plays an important role in the development of diabetic complications including metabolic abnormality-induced diabetic micro-vascular and macro-vascular complications. urtica dioica l. (u. dioica) has been traditionally used in iranian medicine as an herbal remedy for hypoglycemic or due to its anti-inflammatory properties. the aim of the present study was to evaluate...

conclusions the findings confirmed the positive influence of ud supplements and aerobic training on glycemic control in males with t2dm. when aerobic training was combined with a ud supplement, a greater degree of glycemic control was observed. results a significant decrease in fasting blood sugar (fbs) was observed in the ae group (-9.50 ± 6.96 mg/dl; p = 0.002), the ud group (-7.60 ± 6.04 mg/...

background: urtica dioica has been used as antihypertensive, antihyperlipidemic and antidiabetic herbal medicine. the purpose of this study was to study the effect of hydroalcoholic extract of urtica dioica on fructose-induced insulin resistance rats. methods: forty male wistar rats were randomly divided into five groups including control, fructose, extract 50, extract 100 and extract 200. the ...

Objectives: Since decades plant extracts belong to the most popular drugs for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH)/benign prostatic enlargement (BPE). Herein we review biological mechanisms, the placebo effect, results of clinical trials, the role of meta-analyses and guideline recommendations. Methods: Review of the literature with particular reference ...