BACKGROUND Misoprostol has been extensively researched for its use in obstetrics and has proved to be a very effective cervical softening agent before termination of pregnancy. The beneficial effects on cervical ripening may make misoprostol a desirable agent for helping cervical dilatation on non pregnant women also. The objective is to study the efficacy of preoperative vaginal application of...

OBJECTIVES To compare three methods of labour induction. DESIGN Randomised controlled trial. SETTING Academic hospitals in Johannesburg, South Africa. SUBJECTS Women with intact membranes due for induction of labour. METHOD Randomised, sealed opaque envelopes were used to allocate women to labour induction with extra-amniotic Foley catheter/titrated oral misoprostol solution (N = 174), ...

Objectives To investigate the efficacy and safety of misoprostol in the induction of labor at term by comparing this agent with the commonly used dinoprostone gel. Patients and methods A randomized clinical trial of vaginal misoprostol, 50 μg 6-hourly, and dinoprostone gel, 1–2 mg 6-hourly, in 435 women undergoing induction of labor at term. The women, 210 in the misoprostol group and 225 in th...

background with the advent of hystroscopic surgery, abnormalities confined to the uterine cavity such as endometrial polyps, submucous myomas, uterine septae and synechia , were supposed to be treated effectively. diagnostic hysteroscopy is the gold standard for investigating the intrauterine diseases as it allows for biopsy and removal of lesions. objectives forty premenopausal women without t...

OBJECTIVE To evaluate the effectiveness of vaginal misoprostol in overcoming an unsatisfactory colposcopy in the patients who had abnormal cervical cytology and to evaluate side effects of vaginal misoprostol. METHODS Sixty patients with an unsatisfactory colposcopy during the period of September 2007-November 2008 were recruited and randomly allocated to receive either two tablets of 200 mic...

OBJECTIVE To analyze the misoprostol use in pregnancies with intrauterine fetal death (IUFD), considering mode of delivery and induction-delivery interval. METHODS Descriptive study including 171 pregnant women with IUFD, in the second or third trimester, submitted to labor induction with vaginal misoprostol and/or induction/augmentation with intravenous oxytocin, from 2005 to 2008, at a teac...

METHOD(S) : In our tertiary referral hospital, 25 mg vaginal misoprostol 6 hourly for a maximum of five doses and 50 μg oral misoprostol 6 hourly for a maximum of five doses were compared with 0.5mg intracervical dinoprostone gel 12 hourly for a maximum of three doses for induction of labor at term in 150 women in three groups of 50 each. Number of vaginal deliveries achieved, induction to vagi...

background: intrauterine insemination (iui) is one of the most appropriate and cost-effective methods in infertility treatment. objective: we aimed to investigate effect of vaginal misoprostol on pregnancy rate after iui. materials and methods: two hundred and ten infertile women who were referred to infertility clinic of alzahra hospital by an indication of iui during 2012-2013 were randomly a...

To compare the efficacy and safety of two misoprostol dosing regimens for induction of labour in primiparous (1P) and multiparous (>1P) women. METHODS Retrospective study of induction of labour using vaginal misoprostol 25 �g vs. 50 �g every 6 h in 942 women at a tertiary centre. The main outcome variables are induction-to-delivery interval, latency period duration, vaginal delivery within 24 h...

BACKGROUND In China, no multicenter double-blinded prospective randomized controlled study on labor induction has been conducted till now. This study is to evaluate the efficacy and safety of intravaginal accurate 25-μg misoprostol tablets for cervical ripening and labor induction in term pregnancy in nulliparous women. METHODS This was a double-blinded, prospective randomized controlled stud...