Vaginal drug administration can improve prophylaxis and treatment of many conditions affecting the female reproductive tract, which includes fungal bacterial infections, sexually transmitted diseases cancer also. This is best route for proteins, peptides, also other therapeutic drugs like macro-molecules. For contraceptives, steroids, metronidazole, anti-retroviral, vaginal delivery most prefer...

OBJECTIVE To determine Turkish women's opinion about vaginal birth. MATERIALS AND METHODS This prospective cohort study was conducted in Department of Obstetrics and Gynecology of Süleymaniye Maternity Research and Training Hospital in İstanbul, Turkey, between February 2015 and April 2015. The participants of this study were 100 primiparous pregnant women who had vaginal deliveries. The wome...

Testosterone defi ciency occurs during menopause and may be associated with the appearance of a variety of symptoms in addition to its negative effect on sexuality. In the present study, testosterone was administered in the vulval/vaginal region at a dose of 3 mg/ml dissolved in a Pentravan® emulsion (Fagron, the Netherlands) to patients with symptoms of androgen defi ciency and testosterone le...

STUDY QUESTION Can sublingual administration of misoprostol 1 h prior to vacuum aspiration be more effective than vaginal administration and as effective as either route three 3 h prior to surgery? SUMMARY ANSWER Sublingually administered misoprostol is superior to vaginally administered misoprostol when given 1 h pre operatively, and it is as effective as after a three 3 h priming interval w...

Until recently, surgical treatment of a benign adnexal mass implied a laparotomy. In recent years, the development of laparoscopic surgery, as well as ultrasound-guided aspiration techniques, have significantly modified the treatment options for these patients. These procedures have shown considerable advantages. They have reduced surgical trauma and have shortened the hospital stay. We present...

BACKGROUND To compare neonatal mortality and neurodevelopmental outcomes at two years of age in very low birth weight infants (≤1500 g) born by cesarean with those by vaginal delivery. METHODS In this retrospective, case-control study, we evaluated neonatal mortality, medical conditions and neurodevelopmental outcomes at two years of corrected age in 710 very low birth weight (VLBW) infants b...

In an appropriate clinical setting and properly selected group of women, VBAC offers distinct advantages over a repeat caesarean section, since the operative risks are completely eliminated, the hospital stay is much shorter and expenses involved are much less. Trial of labour after previous caesarean delivery (TOLAC) provides women who desire a vaginal delivery with the possibility of achievin...

Over the last 40 years, evidence has accumulated to suggest the ubiquitous presence of infections with intracellular bacteria of the genus Chlamydia in different livestock species. Different methods to clinical specimens substantiated such widespread, but mostly clinically unapparent, presumably low-level infections. In this initial epidemiological study, we addressed the question of chlamydial...

Objectives: 1) To study the feasibility of performing and outcome of vaginal hysterectomy in uteri without any descent and associated with benign ovarian tumour. 2) To compare the outcome of vaginal hysterectomy over hysterectomy performed through abdominal route and laparoscopically. Methodology: Three hundred (300) patients requiring pan hysterectomy for benign ovarian tumours were studied wi...

Objective: To evaluate the applicability of the technique of vaginal hysterectomy in non-prolapsed uterus. Methods: A retrospective cohort study with 220 patients submitted to vaginal hysterectomy from January 2004 to July 2010 by the Vaginal Surgery and Pelvic Floor Team. Patients mean age was 44.4 years and they had on average three births (0-10 deliveries). The surgery was performed even in ...